16503-79-0Relevant academic research and scientific papers
A general strategy for construction of a difluoromethyl compound library and its application in synthesis of pseudopeptides bearing a terminal difluoromethyl group
Wu, Jingjing,Cao, Song,Liu, Nianjin,Shen, Li,Yu, Jinlong,Zhang, Jian,Li, Hui,Qian, Xuhong
experimental part, p. 2386 - 2391 (2010/07/09)
We describe the development of a novel synthesis strategy that uses common reaction conditions to transform a collection of simple building blocks into complex molecules bearing a terminal difluoromethyl group. The core of this approach is the conscious design and synthesis of new difluorinated building blocks which contain inactive and reactive groups on each side of the CF 2 group. The strategy is illustrated by application to the synthesis of CF2H-bearing pseudopeptides via Ugi reaction.
Adsorption effects on the selective electrofluorination of α-(phenylthio)acetamides and α-(phenylthio)acetates in Et3N·3HF/CH3CN
Suryanarayanan,Chellammal,Noel
, p. 53 - 59 (2007/10/03)
Cyclic voltammetric behaviour of α-(phenylthio)acetamides and α-(phenylthio)acetates were compared in CH3CN/tetrabutylammonium perchlorate (TBAP) and CH3CN/Et3N·3HF to assess the influence of fluoride ion on the oxidative
Electrolytic Partial Fluorination of Organic Compounds. 17. Regiospecific Anodic Fluorination of Sulfides Bearing Electron-Withdrawing Substituents at the Position α to the Sulfur Atom
Fuchigami, Toshio,Shimojo, Moriyasu,Konno, Akinori
, p. 3459 - 3464 (2007/10/02)
Regiospecific monofluorination of various sulfides bearing electron-withdrawing substituents, cyano, ester, acyl, amino, and phosphonate groups, at their α-positions was successfully carried out by the anodic oxidation of the sulfides in Et3N*3HF/MeCN usi
Electrolytic Partial Fluorination of Organic Compounds. Regioselective Anodic Monofluorination of Organosulfur Compounds
Fuchigami, Toshio,Shimojo, Moriyasu,Konno, Akinori,Nakagawa, Kiyono
, p. 6074 - 6075 (2007/10/02)
Regioselective anodic monofluorination of aryl 2,2,2-trifluoroethyl sulfides gave, exclusively, aryl 1,2,2,2-tetrafluoroethyl sulfides, the products of fluorination at the position α to the trifluoromethyl group.The α-monofluorination of sulfides bearing
