165036-41-9Relevant academic research and scientific papers
Diastereoselective addition of imidazolidin-2-one controlled enolates to activated imines
Roos, Gregory H. P.,Balasubramaniam, Sundari
, p. 755 - 762 (2007/10/03)
Ephedrine-based imidazolidin-2-one chiral auxiliaries afford good syn stereoselectivity in the addition of their derived titanium enolates with an activated imine system. This provides entry into β-amino acid systems.
Addition to activated imines of enolates from chiral N-acyloxazolidinones
Abrahams, Isaac,Motevalli, Majid,Robinson, Andrew J.,Wyatt, Peter B.
, p. 12755 - 12772 (2007/10/02)
The lithium and titanium enolates of N-acyloxazolidinones 1a-c add in their chelated forms to PhCH=NTs, to give stereoselectively the β-amino acid derivatives 3a-c and 4a-c. The relative configurations of the newly created chiral centres were established
