141022-85-7

Upstream product

• 16251-45-9 (4S,5R)-4-methyl-5-phenyl-oxazolidin-2-one 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 164913-53-5 (4S,5R)-3-<(2R,3S)-2,3-diphenyl-3-(tosylamino)propionyl>-4-methyl-5-phenyloxazolidin-2-one 
• 165036-41-9 (4S,5R)-3-<(2R,3R)-2,3-diphenyl-3-(tosylamino)propionyl>-4-methyl-5-phenyloxazolidin-2-one 
• 202932-19-2 (S)-4-((4S,5R)-4-Methyl-2-oxo-5-phenyl-oxazolidin-3-yl)-4-oxo-3-phenyl-butyric acid tert-butyl ester 
• 161583-20-6 [(R)-3-((4S,5R)-4-Methyl-2-oxo-5-phenyl-oxazolidin-3-yl)-3-oxo-2-phenyl-propyl]-carbamic acid benzyl ester 
• 63818-95-1 S(+)-acide fluoro-2 phenyl-2 acetique 
• 63818-94-0 (R)-α-fluoro-α-phenylacetic acid 
• 202932-25-0 (S)-4-((4S,5R)-4-Methyl-2-oxo-5-phenyl-oxazolidin-3-yl)-4-oxo-3-phenyl-butyric acid 
• 1040-59-1 (R)-3-Benzyloxycarbonylamino-2-phenyl-propionic acid 
• 1008-63-5 (R)-α-phenyl-β-alanine 
• 16251-45-9 (4S,5R)-4-methyl-5-phenyl-oxazolidin-2-one 
• 141022-92-6 (4S,5R)-3-(2-Fluoro-2-phenyl-acetyl)-4-methyl-5-phenyl-oxazolidin-2-one 
• 177031-01-5 (S)-3-Cyano-2-phenylpropanoic acid 
• 177187-82-5 (S)-4-amino-2-phenylbutanoic acid 

Relevant academic research and scientific papers

Synthesis of constrained bicyclic dipeptide mimetics

An efficient synthesis of constrained bicyclic peptidomimetics of (R)-Phe-Pro dipeptide is described, Such mimetics may provide an opportunity to develop inhibitors of thrombin possessing the desired pharmacological features.

Enantioselective synthesis of 2-substituted 4-aminobutanoic acid (GABA) analogues via cyanomethylation of chiral enolates

Cyanomethylation by bromoacetonitrile of sodium or lithium enolates derived from (4S,5R)-3-acyl-4-methyl-5-phenyl-1,3-oxazolidin-2-ones usually shows good stereoselecrivity; although the reaction of 3-(3-carboxypropanoyl)oxazolidinone 5d is exceptionally