16513-67-0 Usage
Description
2-Hydroxy-5-nitroindane, a chemical compound with the molecular formula C9H7NO3, is a substituted indane derivative characterized by the presence of a hydroxy group at the 2nd position and a nitro group at the 5th position. 2-HYDROXY-5-NITROINDANE has garnered interest due to its potential applications in various fields, including pharmaceuticals, dyes, and material science.
Uses
Used in Pharmaceutical Development:
2-Hydroxy-5-nitroindane is utilized as a building block in the synthesis of bioactive molecules, contributing to the development of new pharmaceuticals. Its unique structure allows for the creation of diverse chemical entities with potential therapeutic properties.
Used in Dye Production:
In the dye industry, 2-Hydroxy-5-nitroindane serves as an intermediate in the production of organic pigments. Its chemical properties make it a valuable component in the synthesis of dyes with specific color characteristics and stability.
Used in Material Synthesis:
2-Hydroxy-5-nitroindane also holds potential in the synthesis of novel materials, where its structural features can be leveraged to create materials with unique properties. This application is still in the research phase, with ongoing studies aimed at understanding its full potential in material science.
While the applications of 2-Hydroxy-5-nitroindane are promising, further research is necessary to fully explore its properties and optimize its use in these industries.
Check Digit Verification of cas no
The CAS Registry Mumber 16513-67-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,5,1 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 16513-67:
(7*1)+(6*6)+(5*5)+(4*1)+(3*3)+(2*6)+(1*7)=100
100 % 10 = 0
So 16513-67-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H9NO3/c11-9-4-6-1-2-8(10(12)13)3-7(6)5-9/h1-3,9,11H,4-5H2
16513-67-0Relevant articles and documents
THIENODIAZEPINE DERIVATIVES AND APPLICATION THEREOF
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Paragraph 0232-0234, (2020/08/09)
The present invention relates to a class of thienodiazepine derivatives and an application thereof in the preparation of a drug for the treatment of diseases associated with bromodomain and extra-terminal (BET) Bromodomain inhibitors. Specifically, the present invention relates to compounds represented by formulas (I) and (II), as well as pharmaceutically acceptable salts thereof.
Design, synthesis and evaluation of indene derivatives as retinoic acid receptor α agonists
Guan, Xianghong,Luo, Peihua,He, Qiaojun,Hu, Yongzhou,Ying, Huazhou
, (2017/01/24)
A series of novel indene-derived retinoic acid receptor α (RARα) agonists have been designed and synthesized. The use of receptor binding, cell proliferation and cell differentiation assays demonstrated that most of these compounds exhibited moderate RARα binding activity and potent antiproliferative activity. In particular, 4-((3-isopropoxy-2,3-dihydro-1H-inden-5-yl)-carbamoyl) benzoic acid (36d), which showed a moderate binding affinity, exhibited a great potential to induce the differentiation of NB4 cells (68.88% at 5 μM). Importantly, our work established indene as a promising skeleton for the development of novel RARα agonists.
HETEROCYCLIC COMPOUNDS AND METHODS OF USE
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Paragraph 0448, (2015/05/05)
The present application discloses compounds that are inhibitors of Btk, compounds that are inhibitors of ΡΒΚδ, and compounds that are dual inhibitors of both Btk and PI3Kδ. Also described are methods for synthesizing such inhibitors and methods for using such inhibitors for the treatment of diseases wherein inhibition of Btk and PI3Kδ provides a therapeutic benefit to a patient having the disease.
