165184-98-5

Basic information

• Product Name: Octanal, 2-(phenylmethylene)-, (2E)-
• Synonyms: EC 639-566-4
• CAS NO: 165184-98-5
• Molecular Formula: C15H20O
• Molecular Weight: 216.323
• Mol File: 165184-98-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 308.1±0.0 °C(Predicted)
• Density: 0.954±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Octanal, 2-(phenylmethylene)-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Octanal, 2-(phenylmethylene)-, (2E)-(165184-98-5)
• EPA Substance Registry System: Octanal, 2-(phenylmethylene)-, (2E)-(165184-98-5)

Safety Data

• Hazardous Substances Data: 165184-98-5(Hazardous Substances Data)

Upstream product

• 124-13-0 Octanal 
• 100-52-7 benzaldehyde 
• 1120-48-5 n-dioctylamine 
• 201230-82-2 carbon monoxide 
• 16967-02-5 1-phenyl-1-octyne 
• 591-50-4 iodobenzene 
• 629-05-0 n-octyne 
• 123-72-8 butyraldehyde 

Downstream Products

• 144407-12-5 (E)-(4R,5R)-2-(1-Hexyl-2-phenyl-1-ethenyl)-4,5-dicarboethoxy-1,3-dioxolane 
• 1256954-74-1 (E)-(2-(2,2-dichlorovinyl)oct-1enyl)benzene 
• 1589518-79-5 N-(2-hexyl-1H-inden-1-yl)-4-methylbenzenesulfonamide 
• 1456893-28-9 methyl (±)-3-[(2-formyl-1-phenyloctyl)sulfanyl]propanoate 
• 17744-29-5 2-hexyl-3t-phenyl-acrylaldehyde-semicarbazone 

Relevant articles and documents

Syngas-Free Highly Regioselective Rhodium-Catalyzed Transfer Hydroformylation of Alkynes to α,β-Unsaturated Aldehydes

The hydroformylation of alkynes is a fundamental and important reaction in both academic research and industry. Conventional methods focus on the conversion of alkynes, CO, and H2 into α,β-unsaturated aldehydes, but they often suffer from problems associated with operation, regioselectivity, and chemoselectivity. Herein, we disclose an operationally simple, mild, and syngas-free rhodium-catalyzed reaction for the hydroformylation of alkynes via formyl and hydride transfer from an alkyl aldehyde. This synthetic method uses inexpensive and easy-to-handle n-butyraldehyde to overcome the challenge posed by the use of syngas in traditional approaches and employs a commercially available catalyst and ligand to transform a broad range of internal alkynes, especially alkynyl-containing complex molecules, into versatile stereodefined α,β-unsaturated aldehydes with excellent chemo-, regio-, and stereoselectivity.

Binuclear Pd(I)-Pd(I) Catalysis Assisted by Iodide Ligands for Selective Hydroformylation of Alkenes and Alkynes

Since its discovery in 1938, hydroformylation has been thoroughly investigated and broadly applied in industry (>107 metric ton yearly). However, the ability to precisely control its regioselectivity with well-established Rh- or Co-catalysts has thus far proven elusive, thereby limiting access to many synthetically valuable aldehydes. Pd-catalysts represent an appealing alternative, yet their use remains sparse due to undesired side-processes. Here, we report a highly selective and exceptionally active catalyst system that is driven by a novel activation strategy and features a unique Pd(I)-Pd(I) mechanism, involving an iodide-assisted binuclear step to release the product. This method enables β-selective hydroformylation of a large range of alkenes and alkynes, including sensitive starting materials. Its utility is demonstrated in the synthesis of antiobesity drug Rimonabant and anti-HIV agent PNU-32945. In a broader context, the new mechanistic understanding enables the development of other carbonylation reactions of high importance to chemical industry.

Diphenylboron perchlorate as an efficient catalyst for self- and cross-condensation reactions of aldehydes having α-active hydrogens

Diphenylboron perchlorate very smoothly catalyzed self- and cross-condensation reactions of aldehydes at rt in nitroethane. The new catalyst provided novel behaviors owing to the characteristics of possessing a covalency in the boron-oxygen bond, compared with ionic perchlorates.