165271-67-0

Upstream product

• 166049-80-5 dibenzyl <<(benzyloxy)(chloromethyl)phosphinoyl>methyl>phosphonate 
• 15205-57-9 tribenzyl phosphite 
• 165271-66-9 tetrabenzyl <<(benzyloxy)phosphoryl>bis(methylene)>bis(phosphonate) 
• 29134-54-1 tris(benzyloxy)methane 

Downstream Products

• 174571-56-3 3'-azido-3'deoxy-5'-O{[(bis-benzyloxyphosphorylmethyl)benzyloxyphosphorylmethyl]benzyloxyphosphoryl}-N³-{1-[5-(2,2,2-trifluoroacetylamino)pentyl]}thymidine 

Relevant academic research and scientific papers

An unsymmetrical approach to the synthesis of bismethylene triphosphate analogues

(Chemical Equation Presented) A protected, unsymmetrical bismethylene triphosphate analogue was prepared by sequential Michaelis-Arbuzov reactions on ethyl bis(halomethyl)phosphinates. This species was monodeprotected at one of the terminal phosphonate gr

First Use of Benzyl Phosphites in the Michaelis-Arbuzov Reaction Synthesis of Mono-, Di-, and Triphosphate Analogs

Benzyl phosphites were used in the Michaelis-Arbuzov reaction.Special experimental conditions allowed preparation of a set of phosphonate analogs of mono-, di-, and triphosphate.Furthermore, regioselective mono-deprotection mades these molecules useful building blocks for the synthesis of analogs of polyphosphorylated compounds of biological interest (e.g. nucleotides), after removal of all phosphonate benzyl ester groups under very mild conditions and high yields.