16546-08-0

Basic information

• Product Name: (2E)-2-[1-(4-methoxyphenyl)ethylidene]hydrazinecarbothioamide
• CAS NO: 16546-08-0
• Molecular Formula: C₁₀H₁₃N₃OS
• Molecular Weight: 223.2947
• Mol File: 16546-08-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 360.392°C at 760 mmHg
• Flash Point: 171.759°C
• Density: 1.209g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: (2E)-2-[1-(4-methoxyphenyl)ethylidene]hydrazinecarbothioamide(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-2-[1-(4-methoxyphenyl)ethylidene]hydrazinecarbothioamide(16546-08-0)
• EPA Substance Registry System: (2E)-2-[1-(4-methoxyphenyl)ethylidene]hydrazinecarbothioamide(16546-08-0)

Safety Data

• Hazardous Substances Data: 16546-08-0(Hazardous Substances Data)

Usage

General Description

The chemical compound (2E)-2-[1-(4-methoxyphenyl)ethylidene]hydrazinecarbothioamide, also known as 4-methoxyphenyl ethylidene hydrazinecarbothioamide, is an organic compound with the molecular formula C10H13N3OS. It is a thiosemicarbazone derivative, containing a hydrazine group and a thiocarbonyl functional group. (2E)-2-[1-(4-methoxyphenyl)ethylidene]hydrazinecarbothioamide may have potential biological activities and has been investigated for its potential pharmaceutical applications, specifically as an anti-cancer and anti-microbial agent. Its structure and properties make it a promising candidate for further research and development in the field of medicinal chemistry.

Upstream product

• 4346-94-5 thiosemicarbazide hydrochloride 
• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 79-19-6 thiosemicarbazide 
• 2475-92-5 4-methoxyacetophenone oxime 

Downstream Products

• 1516632-25-9 1-(1-p-methoxyphenyl)ethylidene-2-[4-(5-methyl-1-p-tolyl-1,2,3-triazol-4-yl)thiazol-2-yl]hydrazine 
• 80412-62-0 C₁₉H₂₃N₅O₂S*ClH 
• 80412-60-8 C₁₇H₁₈ClN₅OS*ClH 
• 80412-63-1 C₁₈H₂₁N₅OS*ClH 
• 80412-61-9 C₁₈H₂₁N₅OS*ClH 
• 80412-59-5 C₁₇H₁₉N₅OS*ClH 

Relevant articles and documents

Microwave-assisted Vilsmeier-Haack synthesis of Pyrazole-4-carbaldehydes

The synthesis of 4-formylpyrazoles using Vilsmeier-Haack reagent is a common protocol in pyrazole chemistry. An efficient microwave-assisted synthesis of 4-formylpyrazoles by employing Vilsmeier-Haack reagent (OPC-VH) derived from phthaloyl dichloride/dimethylformamide has been described. This method offers the advantages of operational simplicity, avoiding the use of POCl3 as toxic reagents and reuse of the by-product in the preparation of phthaloyl dichloride.

VO(acac)2/H2O2 Mediated Oxidation of 1-(Thiazol-2-yl)-1H-pyrazole-4-carbaldehydes

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Synthesis, molecular docking, acetylcholinesterase and butyrylcholinesterase inhibitory potential of thiazole analogs as new inhibitors for Alzheimer disease

A series of thirty (30) thiazole analogs were prepared, characterized by 1H NMR, 13C NMR and EI-MS and evaluated for Acetylcholinesterase and butyrylcholinesterase inhibitory potential. All analogs exhibited varied butyrylcholinester