1655-54-5 Usage
Uses
Used in Biochemical Research:
N-(2,4-Dinitrophenyl)-L-phenylalanine is used as a chiral derivatizing agent for the analysis of amino acids in biological samples. It aids in the separation and identification of enantiomers, which is crucial for understanding the stereochemistry of biological molecules and their interactions.
Used in Pharmaceutical Development:
In the pharmaceutical industry, N-(2,4-Dinitrophenyl)-L-phenylalanine is utilized as a tool for the analysis of chiral compounds. Its application contributes to the development of drugs with specific stereochemistry, ensuring the desired biological activity and minimizing potential side effects associated with the incorrect enantiomer.
Used in Chromatography and Spectrometry:
N-(2,4-Dinitrophenyl)-L-phenylalanine is employed as a derivatizing agent in chromatographic and spectrophotometric techniques. It enhances the detection and quantification of amino acids by altering their physical and chemical properties, making them more suitable for analysis through these methods. This application is vital for accurate and precise measurements in various scientific and clinical settings.
Check Digit Verification of cas no
The CAS Registry Mumber 1655-54-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,5 and 5 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1655-54:
(6*1)+(5*6)+(4*5)+(3*5)+(2*5)+(1*4)=85
85 % 10 = 5
So 1655-54-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H13N3O6/c19-15(20)13(8-10-4-2-1-3-5-10)16-12-7-6-11(17(21)22)9-14(12)18(23)24/h1-7,9,13,16H,8H2,(H,19,20)/t13-/m0/s1
1655-54-5Relevant academic research and scientific papers
Efficient nucleophilic substitution reaction of aryl halides with amino acids under focused microwave irradiation
Cherng, Yie-Jia
, p. 8287 - 8289 (2007/10/03)
The nucleophilic substitution reaction of 2,4-dinitrofluorobenzene with amino acids was complete, under microwave iradiation, within 40 s with yields up to 93%, which are far superior to those obtained under conventional heating. (C) 2000 Elsevier Science Ltd.
Simple and efficient preparation of (R)- and (S)-enantiomers of α-carbon deuterium-labelled α-amino acids
Mitulovi, Goran,Laemmerhofer, Michael,Maier,Lindner, Wolfgang
, p. 449 - 461 (2007/10/03)
A procedure for the synthesis of (R)- and (S)-enantiomers of α-carbon deuterium-labelled α-amino acids, exemplified for (R)- and (S)-[2-2H1]-Leu is described. Starting from the respective (S)- or (R)-enantiomer or from the racemic mixture of an α-amino acid the selective proton exchange at the α-carbon is carried out by racemization via a Schiff base in monodeuterated acetic acid as solvent which serves as deuterium source. After N-protection the racemic mixture is liquid chromatographically separated into the individual (R)- and (S)-enantiomers on preparative scale employing a chiral anion exchanger based on carbamoylated quinine as chiral selector. After deprotection the enantiomerically pure products can be obtained in good yields.
