16562-77-9

Usage

Uses

Used in Chemical Synthesis:
Sodium 2-oxopropanesulphonate is used as an intermediate in the synthesis of Sodium Dibromomethanesulfonate (S624110). sodium 2-oxopropanesulphonate is utilized in the preparation of halogenated alkyl sulfonic acids, which are essential in the production of Rontgen photographs of urogenital organs.

InChI:InChI=1/C3H6O4S.Na/c1-3(4)2-8(5,6)7;/h2H2,1H3,(H,5,6,7);/q;+1/p-1

Upstream product

• 78-95-5 chloroacetone 
• 598-31-2 1-bromoacetone 

Downstream Products

• 127-09-3 sodium acetate 
• 2386-57-4 methanesulfonic acid sodium salt 

Relevant academic research and scientific papers

Synthetic Studies towards CH-Diazomethane Sulfonamides: a Novel Type of Diazo Reagents

Preparation of CH-diazomethane sulfonamides has been developed for the first time. Their utility as a new type of diazo reagents was showcased in cycloaddition reactions with electron-deficient alkynes and β-nitro styrenes which delivered medicinally important pyrazole-3-sulfonamides in good to excellent yields.

PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES

Described herein are pyrrolo{2,3-d}pyrimidine derivatives, their use as Janus Kinase (JAK) inhibitors, and pharmaceutical compositions containing them.

CASPASE 6 INHIBITORS AND USES THEREOF

Disclosed herein, inter alia, are compounds and methods for inhibiting Caspase 6 and the treatment of diseases, pharmaceutical composition including a compound as described herein and a pharmaceutically acceptable excipient and methods of inhibiting human Caspase 6 protein activity, the method including: contacting the human Caspase 6 protein with a compound as described herein.

NOVEL INHIBITORS OF PROTEIN KINASES

Protein kinases are regulators of cellular signaling and their functional dysregulation is common in carcinogenesis and many other disease states or disorders. The present invention relates to novel chemical entities that have biological activity to modulate mammalian protein kinase enzymes. In particular, compounds of the invention display potent inhibition of breast tumor related kinase (BRK).

Specific intramolecular aromatic C–H insertion of diazosulfonamides

The chemoselectivity in the intramolecular C–H insertion of various diazosulfonamides has been experimentally studied. The results reveal that the aliphatic 1,4-, 1,5-, or 1,6-C(sp3)?H insertions of diazosulfonamides are not accessible, while t

COMPOUNDS AND METHODS FOR CONTROLLING BACTERIAL VIRULENCE

Novel sulfonated homoserine lactones formula I have been found to act ac quorum sensing inhibitors. As such, they may be useful in the treatment of bacterial infections.

New heterocyclic precursors for thermal generation of reactive, electron-rich 1,2-diaza-1,3-butadienes

Figure presented The preparation and thermolysis of new stable heterocyclic precursors of 1,2-diaza-1,3-butadienes is described. The resulting reactive diazadienes are trapped in situ with N-phenyldiazamaleimide. The effect of precursor structure on the temperature at which the diazadienes are generated is discussed.