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6-Bromo-8-chloroquinoline, a heterocyclic aromatic compound with the molecular formula C9H5BrClN, features both bromine and chlorine atoms on its quinoline ring. This unique structure endows it with versatile chemical properties and reactivity, making it a valuable building block in the synthesis of biologically active compounds and pharmaceuticals.

16567-13-8

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16567-13-8 Usage

Uses

Used in Pharmaceutical Industry:
6-Bromo-8-chloroquinoline is used as a key intermediate in the synthesis of various biologically active compounds for the development of new drugs. Its unique structure allows for the creation of pharmaceuticals with potential applications in the treatment of a wide range of diseases.
Used in Organic Synthesis:
6-Bromo-8-chloroquinoline is utilized as an important intermediate in organic synthesis processes. Its chemical properties and reactivity contribute to the development of new compounds and materials with diverse applications across various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 16567-13-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,5,6 and 7 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 16567-13:
(7*1)+(6*6)+(5*5)+(4*6)+(3*7)+(2*1)+(1*3)=118
118 % 10 = 8
So 16567-13-8 is a valid CAS Registry Number.

16567-13-8Downstream Products

16567-13-8Relevant articles and documents

From Anilines to Quinolines: Iodide- and Silver-Mediated Aerobic Double C?H Oxidative Annulation–Aromatization

Wu, Jiwei,Liao, Zhixiong,Liu, Dong,Chiang, Chien-Wei,Li, Zheng,Zhou, Zhonghao,Yi, Hong,Zhang, Xu,Deng, Zixin,Lei, Aiwen

supporting information, p. 15874 - 15878 (2017/10/23)

Quinoline synthesis from easily accessible raw materials such as anilines is a valuable and meaningful task. Herein, we communicate an iodide- and silver-mediated C?H/C?H oxidative annulation–aromatization between anilines and allyl alcohols. This protocol provides a direct route to the synthesis of quinoline derivatives from inexpensive commodities. Various kinds of anilines, even heterocyclic anilines, were shown to be workable substrates, generating the corresponding multi-substituted quinolines in good yields.

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