165673-48-3Relevant academic research and scientific papers
A Difference CD Method for Determining Absolute Stereochemistry of Acyclic 1,2,4-Triols
Mori, Yuji,Furukawa, Hiroshi
, p. 6725 - 6738 (2007/10/02)
A general method based on difference circular dichroic (DIF CD) spectroscopy for assigning the absolute configuration of 1,2,4-triol is presented.Four possible stereoisomers of 6-heptene-1,2,4-triol were prepared and served as models to develop the procedure.The sign of the DIF CD Cotton effect is correlated to the absolute configuration of the C2 position.
A NEW SYNTHETIC APPROACH TO (R)-GABOB FROM L-MALIC ACID
Misiti, Domenico,Zappia, Giovanni,Monache, Giuliano Delle
, p. 219 - 222 (2007/10/02)
A synthesis of (R)-4-amino-3-hydroxybutanoic acid, starting from L-malic acid, is reported.The synthetic approach involves an inversion of configuration of the chiral centre to obtain the correct stereochemistry, together with the protection of the 1,2-am
