16574-51-9Relevant academic research and scientific papers
A novel Br?nsted acid catalyst for Friedel-Crafts acylation
Posternak, Anna G.,Garlyauskayte, Romute Yu.,Yagupolskii, Lev M.
supporting information; body text, p. 446 - 447 (2009/05/27)
Bis(trifluoroalkylsulfonylimino)trifluoromethanesulfonic acid has demonstrated remarkable catalytic ability in the electrophilic acylation of aromatic substrates. Various perfluoroalkyl substituted aroyl chlorides are employed in Friedel-Crafts acylation typically using 1 mol % of catalyst. Crown Copyright
Electrophilic aromatic aroylation with CF3-bearing arenecarboxylic acid derivatives: Reaction behavior and acidic mediator dependence
Akiko, Okamoto,Katsuya, Maeyama,Hideaki, Oike,Noriyuki, Yonezawa
, p. 2701 - 2715 (2008/02/12)
Triflic acid (TfOH) has been proven to be effective as a tolerant acidic mediator in electrophilic aromatic aroylation with CF3-bearing aroyl chlorides. The TfOH-mediated aroylation of fluorobenzene proceeds with high selectivity to give CF3-bearing aryl fluorophenyl ketones in good yields, which are hardly obtained with the aid of AlCl3 or direct condensation reagents. Copyright Taylor & Francis Group, LLC.
