165803-62-3

Upstream product

• 14473-91-7 3-Bromocinnamic acid 
• 65537-54-4 3-(3-bromophenyl)-propan-1-ol 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 852540-83-1 {3-[3-(4-hydroxy-but-1-ynyl)-phenyl]-propyl}-carbamic acid tert-butyl ester 
• 852540-84-2 {3-[3-(4-hydroxy-butyl)-phenyl]-propyl}-carbamic acid tert-butyl ester 
• 852540-85-3 {3-[3-(4-oxo-butyl)-phenyl]-propyl}-carbamic acid tert-butyl ester 
• 852540-82-0 tert-butyl 3-(3-bromophenyl)propylcarbamate 
• 198633-83-9 1-(3-azido-propyl)-3-bromo-benzene 
• 852540-90-0 [3-(3-{5-benzenesulfonyl-5-[7-(tert-butyl-dimethyl-silanyloxymethyl)-naphthalen-2-yl]-4-oxo-pentyl}-phenyl)-propyl]-carbamic acid tert-butyl ester 
• 852540-89-7 [3-(3-{5-benzenesulfonyl-5-[7-(tert-butyl-dimethyl-silanyloxymethyl)-naphthalen-2-yl]-4-hydroxy-pentyl}-phenyl)-propyl]-carbamic acid tert-butyl ester 
• 852540-91-1 [3-(3-{5-[7-(tert-butyl-dimethyl-silanyloxymethyl)-naphthalen-2-yl]-4-oxo-pentyl}-phenyl)-propyl]-carbamic acid tert-butyl ester 
• 852540-92-2 7-{5-[3-(3-tert-butoxycarbonylamino-propyl)-phenyl]-2-oxo-pentyl}-naphthalene-2-carboxylic acid 
• 852541-12-9 (3-{3-[5-(7-hydroxymethyl-naphthalen-2-yl)-4-oxo-pentyl]-phenyl}-propyl)-carbamic acid tert-butyl ester 
• 852540-93-3 7-{5-[3-(3-amino-propyl)-phenyl]-2-oxo-pentyl}-naphthalene-2-carboxylic acid 

Relevant academic research and scientific papers

Enzymatic approach to unnatural glycosides with diverse aglycon scaffolds using glycosyltransferase VinC

Glycosyltransferase VinC was explored for a construction of glycoside libraries using dTDP-vicenisamine and structurally unrelated unnatural aglycons, and new unnatural vicenisaminides were successfully constructed. Structural elements of aglycon recognit

ALKYNYL PHENYL DERIVATIVE COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS

Provided are alkynyl phenyl derivative compounds, pharmaceutical compositions thereof, and methods of treating ophthalmic diseases and disorders, such as age-related macular degeneration and Stargardt's Disease, using said compounds and compositions.

DERIVATIVES OF ALKYLPIPERAZINE AND ALKYLHOMOPIPERAZINE-CARBOXYLATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS

The present invention comprises alkylpiperazine- and alkylhomopiperazine carboxylates and their derivatives, methods for their preparation and the therapeutic use thereof as fatty acid amido hydrolase (FAAH) enzyme inhibitors. These derivatives exert various pharmacological activities by interacting, inter alia, with cannabinoid and vanilloid receptors. By inhibiting the metabolic activity of the FAAH enzyme, compounds often responsible for the onset of disease and other pathological conditions are not generated and the incidence of the disease is greatly reduced.