165807-77-2

Upstream product

• 26190-68-1 1-chloromethyl-2-methylsulfanylbenzene 
• 165807-51-2 ethyl 5-methyl-6-(4-nitrophenyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno<2,3-d>pyrimidine-3-acetate 
• 6186-22-7 4-bromophenyl acetone 
• 165807-45-4 (5-methyl-2,4-dioxo-6-phenyl-1,4-dihydro-2H-thieno[2,3-d]pyrimidin-3-yl)-acetic acid ethyl ester 
• 219547-43-0 2-amino-5-(4-bromo-phenyl)-4-methyl-thiophene-3-carboxylic acid ethyl ester 

Downstream Products

• 165809-27-8 ethyl 5-methyl-1-(2-methylthiobenzyl)-2,4-dioxo-6-(4-propionylaminophenyl)-1,2,3,4-tetrahydrothieno<2,3-d>pyrimidine-3-acetate 
• 165809-12-1 ethyl 6-(4-aminophenyl)-5-methyl-1-(2-methylthiobenzyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno<2,3-d>pyrimidine-3-acetate 

Relevant academic research and scientific papers

Thieno[2,3-d]pyrimidine-3-acetic acids a new class of nonpeptide endothelin receptor antagonists

On the basis of structural information for the cyclic hexapeptide endothelin (ET) receptor antagonist, TAK-044, a series of thieno[2,3- d]pyrimidine-2,4-dione derivatives bearing a carboxyl group and aromatic rings that were important for receptor binding