16587-59-0Relevant academic research and scientific papers
One-pot synthesis using the supported reagent system Na2CO 3/SiO2-PPA/SiO2: Synthesis of Benzo[b]thiophenes and naphthothiophenes
Aoyama, Tadashi,Orito, Mami,Takido, Toshio,Kodomari, Mitsuo
body text, p. 2089 - 2099 (2009/04/03)
A simple and efficient method has been developed for the synthesis of benzo[b]thiophenes and naphtho[2,l-6]thiophenes from arenethiols and α-halo ketones using Na2CO3/SiO2-PPA/ SiO2. Reaction of a-halo ketones with arenethiols is promoted by Na2CO3/SiO2 to afford α-sulfanyl ketones, which cyclize in the presence of PPA/SiO2 to give the corresponding thiophene-fused arenes in one-pot. The reaction using α-bromo acetals instead of α-halo ketones also gave the corresponding naphtho[2,l-b] thiophenes via a three-step reaction in one-pot. Thieme Stuttgart.
One-pot synthesis of benzo[b]thiophenes and naphtho[2,1-b]thiophenes in the presence of acidic and basic supported reagents
Aoyama, Tadashi,Takido, Toshio,Kodomari, Mitsuo
, p. 2739 - 2742 (2007/10/03)
A simple and efficient method has been developed for the synthesis of benzo[b]thiophenes and naphtho[2,1-b]thiophenes from aryl thiols and α-halo ketones by using an acid- and a base-supported reagent system, Na2CO3/SiO2-PPA/SiO2. Reaction of α-halo ketones with aryl thiols is promoted by Na2CO 3/SiO2 to afford α-phenylthio ketones, which cyclizes in the presence of PPA/SiO2 to give the corresponding arylthiophenes in one-pot. Georg Thieme Verlag Stuttgart.
Synthesis of Benzophenalenothiophenes
Pratap, Ram,Castle, Raymond N.,Lee, Milton L.
, p. 439 - 441 (2007/10/02)
The synthesis of both isomers of benzophenalenothiophene namely, benzophenalenothiophene and benzophenalenothiophene is described.
THE ADDITION OF SIMPLE AROMATIC HYDROCARBONS TO CONDENSED AROMATIC THIOpheNES PROMOTED BY ALUMINUM CHLORIDE. PART I. NAPHTHOTHIOPHENE
Clark, Peter David,McKinnon, David M.
, p. 227 - 231 (2007/10/02)
Naphthothiophenes are the major products and at higher temperatures 2-arylnaphthothiophenes rwesult. 1-Arylnaphthothiophenes may be prepard by treatment of the dihydro-addition products with 2,3-dichloro-5,6-dicyano-1,4-benzoquinone thus giving a new synthesis of 1- 2-arylnaphthothiophenes from the parent heterocycle.
