16600-87-6Relevant academic research and scientific papers
Synthesis and structure-activity relationship of 3-arylbenzoxazines as selective estrogen receptor β agonists
Yang, Wu,Wang, Yufeng,Ma, Zhengping,Golla, Rajasree,Stouch, Terry,Seethala, Ramakrishna,Johnson, Susan,Zhou, Rong,Guengoer, Timur,Feyen, Jean H.M.,Dickson Jr., John K.
, p. 2327 - 2330 (2007/10/03)
A series of 3-aryl-7-hydroxybenzoxazine analogues have been prepared and evaluated as ligands for the two estrogen receptor subtypes (ERα and ERβ). From the radioligand binding assay, compounds with more than a 10-fold binding selectivity toward the ERβ s
O-nitrophenyltriflates in quinoline synthesis : Easy access to a streptonigrin synthon
Holzapfel, Cedric W.,Dwyer, Catherine
, p. 215 - 219 (2007/10/03)
An efficient route to a wide range of 2-hydroxyquinolines from o-nitrophenyltriflates via a Heck reaction is reported, with emphasis on the preparation of a synthetic equivalent of the streptonigrin AB ring system.
The nitration of electron-rich aromatics
Dwyer,Holzapfel
, p. 7843 - 7848 (2007/10/03)
The successful mononitration of a variety of electron-rich aromatic substrates is reported, employing either nitronium tetrafluoroborate or 'claycop' as the nitrating agent. Dinitration of four of the substrates was achieved when employing nitronium tetrafluoroborate. Several of the products have previously been prepared only by indirect methods.
