16606-61-4

Basic information

• Product Name: 2,4-Dichlororesorcinol
• Synonyms: 2,4-Dichlororesorcinol;2,4-Dichloro-1,3-benzenediol;1,3-Benzenediol, 2,4-dichloro-;2,4-dichlorobenzene-1,3-diol
• CAS NO: 16606-61-4
• Molecular Formula: C₆H₄Cl₂O₂
• Molecular Weight: 179.00076
• Mol File: 16606-61-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 84.5 °C
• Boiling Point: 255.1°Cat760mmHg
• Flash Point: 108.1°C
• Appearance: /
• Density: 1.624g/cm³
• Vapor Pressure: 0.0104mmHg at 25°C
• Refractive Index: 1.642
• Storage Temp.: 2-8°C
• PKA: 6.81±0.15(Predicted)
• CAS DataBase Reference: 2,4-Dichlororesorcinol(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dichlororesorcinol(16606-61-4)
• EPA Substance Registry System: 2,4-Dichlororesorcinol(16606-61-4)

Safety Data

• Hazardous Substances Data: 16606-61-4(Hazardous Substances Data)

Usage

General Description

2,4-Dichlororesorcinol is a chemical compound that belongs to the family of resorcinols, which are commonly used in the production of hair dyes, cosmetic products, and pharmaceuticals. It is a white crystalline solid that is soluble in water and organic solvents. 2,4-Dichlororesorcinol is often used as a chemical intermediate in the synthesis of various pharmaceuticals and dyes. It has also been studied for its potential antimicrobial and antifungal properties, making it a candidate for use in antimicrobial coatings and treatments. However, 2,4-Dichlororesorcinol can be toxic if ingested or inhaled in large amounts, and proper safety precautions should be taken when handling this chemical.

InChI:InChI=1/C6H4Cl2O2/c7-3-1-2-4(9)5(8)6(3)10/h1-2,9-10H

Upstream product

• 6201-65-6 2-chlororesorcinol 
• 89-86-1 4-hydroxysalicylic acid 
• 59119-79-8 3,5-dichloro-2,4-dihydroxybenzoic acid 
• 2150-47-2 methyl 2,4-dihydroxybenzoate 
• 95-88-5 4-Chlororesorcinol 

Downstream Products

• 1166837-63-3 2',4',5',7'-tetrachloro-6-carboxy-4,7-dichlorofluorescein dipivalate 
• 155911-16-3 2',4',5′,7′-tetrachloro-5(6)-carboxy-4,7-dichlorofluorescein 
• 98555-73-8 3,5-dichloro-2,4-dihydroxybenzaldehyde 
• 155911-15-2 4,7,2',4',5',7'-hexachloro-5-carboxy-fluorescein 

Relevant articles and documents

Octachloro-fluorescein: Synthesis and photosensitizer performance evaluation

Fluorescence image-guided photodynamic therapy (PDT) receives great attention since it provides both the diagnostic and therapeutic information. Theoretically, fluorescence and the photodynamic performance (singlet oxygen) can be traced back to the same o

Aqueous chlorination kinetics and mechanism of substituted dihydroxybenzenes

The initial chlorination kinetics of several substituted dihydroxybenzenes, including chlorinated resorcinol compounds, was studied over the pH range of 2-12 at 22 °C. For each of the resorcinol substrates, the apparent chlorination rates are a minimum in the pH range of 3-6 and a maximum at pH values between 8-11. A mechanism that involves the reaction of HOCl with ArX(OH)2, ArX(OH)O-, and ArX(O-)2, and an acid-catalyzed pathway at pH 2, ArX(OH)O-, and ArX(O-)2, and an acid-catalyzed pathway at pH 4 was proposed to explain this pH dependence. Over natural water pH conditions, the reactions of HOCl with the anion and dianion forms of resorcinol groups are the most important. Although the intrinsic reactivity of HOCl with resorcinol substrates decreases with the extent of chlorine substitution on aromatic ring, the apparent reactivity of HOCl increases for more chlorinated resorcinols. In the presence of excess HOCl, monochloro- and dichloro resorcinol intermediates, therefore, should not accumulate when resorcinol groups undergo chlorine substitution. Linear free energy relationships for the reactivity of HOCl with resorcinols and phenols were developed. The sequential chlorination kinetics of resorcinol up to trichlororesorcinol can now be modeled.