166169-34-2Relevant academic research and scientific papers
Development of highly potent inhibitors of Ras farnesyltransferase possessing cellular and in vivo activity
Leftheris, Katerina,Kline, Toni,Vite, Gregory D.,Cho, Young H.,Bhide, Rajeev S.,Patel, Dinesh V.,Patel, Manorama M.,Schmidt, Robert J.,Weller, Harold N.,Andahazy, Mary L.,Carboni, Joan M.,Gullo-Brown, Johnni L.,Lee, Francis Y. F.,Ricca, Carol,Rose, William C.,Yan, Ning,Barbacid, Mariano,Hunt, John T.,Meyers, Chester A.,Seizinger, Bernd R.,Zahler, Robert,Manne, Veeraswamy
, p. 224 - 236 (2007/10/03)
Analogs of CVFM (a known nonsubstrate farnesyltransferase (FT) inhibitor derived from a CA2A2X sequence where C is cysteine, A is an aliphatic residue, and X is any residue) were prepared where phenylalanine was replaced by (Z)-dehyd
