16624-71-8Relevant academic research and scientific papers
Synthesis of different thio-scaffolds bearing sulfonamide with subnanomolar carbonic anhydrase II and IX inhibitory properties and X-ray investigations for their inhibitory mechanism
Angeli, Andrea,Tanini, Damiano,Capperucci, Antonella,Malevolti, Gianni,Turco, Francesca,Ferraroni, Marta,Supuran, Claudiu T.
, p. 642 - 648 (2018/09/29)
Several new molecules with different thio-scaffolds were designed, synthesised, and evaluated biologically as inhibitors of Carbonic Anhydrases (CAIs). The structure-activity relationship analysis identified thioether derivatives, here reported, as a pote
