1428673-40-8Relevant academic research and scientific papers
Synthesis of different thio-scaffolds bearing sulfonamide with subnanomolar carbonic anhydrase II and IX inhibitory properties and X-ray investigations for their inhibitory mechanism
Angeli, Andrea,Tanini, Damiano,Capperucci, Antonella,Malevolti, Gianni,Turco, Francesca,Ferraroni, Marta,Supuran, Claudiu T.
, p. 642 - 648 (2018)
Several new molecules with different thio-scaffolds were designed, synthesised, and evaluated biologically as inhibitors of Carbonic Anhydrases (CAIs). The structure-activity relationship analysis identified thioether derivatives, here reported, as a pote
4-Substituted-2,3,5,6-tetrafluorobenzenesulfonamides as inhibitors of carbonic anhydrases I, II, VII, XII, and XIII
Dudutiene, Virginija,Zubriene, Asta,Smirnov, Alexey,Gylyte, Joana,Timm, David,Manakova, Elena,Gra?ulis, Saulius,Matulis, Daumantas
, p. 2093 - 2106 (2013/04/24)
A series of 4-substituted-2,3,5,6-tetrafluorobenezenesulfonamides were synthesized and their binding potencies as inhibitors of recombinant human carbonic anhydrase isozymes I, II, VII, XII, and XIII were determined by the thermal shift assay, isothermal
