166249-08-7

Upstream product

• 166249-02-1 Benzoic acid (2R,3R,5S)-2-[3-(2-methoxy-ethoxymethyl)-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl]-5-trityloxymethyl-tetrahydro-thiophen-3-yl ester 
• 166249-00-9 (2S,3aS,9aR)-2-Trityloxymethyl-2,3,3a,9a-tetrahydro-thieno[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one 
• 166249-01-0 Benzoic acid (2R,3R,5S)-2-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-5-trityloxymethyl-tetrahydro-thiophen-3-yl ester 

Downstream Products

• 166249-09-8 1-((2R,3R,5S)-3-Fluoro-5-trityloxymethyl-tetrahydro-thiophen-2-yl)-3-(2-methoxy-ethoxymethyl)-1H-pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Facile fluorination of deoxy-4'-thiopyrimidine nucleosides with 'down' hydroxyl group retention of configuration after fluoride opening of the quaternized N3-MEM anhydronucleosides

Attempted fluorination of 1-(5-O-trityl-3-deoxy-4-thio-β-D-erythro-pentofuranosyl)-3-(2-methoxy ethoxymethyl)uracil (12) and 1-(5-O-trityl-2-deoxy-4-thio-β-D-erythro-pentofuranosyl)-3-(2-methoxy ethoxymethyl)uracil (14) with diethylaminosulfur trifluoride