166264-70-6Relevant academic research and scientific papers
High contrast mechanofluorochromic behavior of new tetraphenylethene-based Schiff base derivatives
Sun, Ting,Cheng, Dandan,Chai, Yongshuai,Gong, Jian,Sun, Mengyu,Zhao, Feng
, (2019)
New tetraphenylethene-based Schiff base ligand (TPE-ND) and its corresponding boronated complex (TPE-NDB) with aggregation-induced emission were designed and synthesized. Results showed that the inhibited C=N isomerization by N, O-chelated BF2
A new aggregation-induced emission fluorescent probe for rapid detection of nitroreductase and its application in living cells
Xu, Gaoping,Tang, Yonghe,Ma, Yanyan,Xu, An,Lin, Weiying
, p. 197 - 201 (2018)
The biological activity of nitroreductase (NTR) is closely related to biological hypoxia status in organisms. The development of effective methods for monitoring the activity of NTR is of great significance for medical diagnosis and tumor research. Toward this goal, we have developed a new aggregation-induced emission (AIE) fluorescence NTR probe TPE-HY used the tetraphenylethene as the fluorophore, and used the nitro group as the NTR recognition site. The probe TPE-HY has many excellent properties, including rapid response, AIE characteristics, high sensitivity and selectivity, and low cytotoxicity. Importantly, the probe TPE-HY is successfully applied to monitor endogenous NTR in living HeLa cells.
Enantioselective Recognition for Many Different Kinds of Chiral Guests by One Chiral Receptor Based on Tetraphenylethylene Cyclohexylbisurea
Xiong, Jia-Bin,Xie, Wen-Zhao,Sun, Jian-Ping,Wang, Jin-Hua,Zhu, Zhi-Hua,Feng, Hai-Tao,Guo, Dong,Zhang, Hui,Zheng, Yan-Song
, p. 3720 - 3726 (2016)
A neutral chiral receptor based on TPE cyclohexylbisurea was synthesized and could discriminate the enantiomers of many different kinds of chiral reagents, including chiral acidic compounds, basic compounds, amino acids, and even neutral alcohols. The 1H NMR spectra disclosed that the ability of chiral recognition could be ascribed to the multiple hydrogen bonds and CH interactions between the TPE urea receptor and the enantiomer of the chiral guest, which led to the selective aggregation of the receptor with one of the two enantiomers. This result exhibited a great potential in enantiomer discernment and high-throughput analysis of enantiomer composition of these chiral analytes by one chiral AIE molecule.
Synthesis and photophysical properties of tetraphenylethylene derivatives as luminescent downshifting materials for organic photovoltaic applications
Barros, Hélio Lopes,Brites, Maria Jo?o,Esteves, Maria Alexandra
, (2021/08/24)
Luminescent Down-Shifting (LDS) is an optical approach applied in several photovoltaic (PV) technologies in which high energy solar radiation is converted to a wavelength region where the response of the photovoltaic devices is better. The use of LDS laye
Anionic fluorescent probe, preparation method and application thereof
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, (2021/05/01)
The invention discloses an anionic fluorescent probe, and a preparation method and an application thereof. The anionic fluorescent probe is prepared by mixing 1-(4-amino) phenyl-1, 2, 2-triphenylethylene with a phenyl isothiocyanate derivative and carrying out a condensation reaction. The fluorescent probe has selectivity on anions and can be used for quantitatively analyzing the recognized anions.
Tetraphenylethylene conjugated: P -hydroxyphenacyl: Fluorescent organic nanoparticles for the release of hydrogen sulfide under visible light with real-time cellular imaging
Parthiban,Pavithra,Reddy, L. Vinod Kumar,Sen, Dwaipayan,Samuel, Melvin S.,Singh, N. D. Pradeep
supporting information, p. 7903 - 7909 (2018/11/21)
Hydrogen sulfide (H2S) behaves like a two-edged sword, at low concentrations it has beneficial and cytoprotective effects, while at higher concentrations it exhibits toxicity. Hence there is a keen interest in developing light responsive H2S donors with a spatio-temporal controlled release. Herein, we report visible light activatable tetraphenylethylene conjugated p-hydroxyphenacyl (TPE-pHP-H2S) nanoparticles for the release of hydrogen sulfide (H2S) with a real time monitoring ability. Our newly designed photoresponsive single component organic nanoparticle based H2S donor is built by integrating the tetraphenylethylene (TPE) moiety and p-hydroxyphenacyl (pHP) group so that it can display both aggregation-induced emission (AIE) and excited state intramolecular proton transfer (ESIPT) properties. Aggregation-induced emission enhancement was exhibited by our TPE-pHP-H2S NP donor, which was then explored for the cellular imaging application. The ESIPT by the pHP moiety provided unique advantages to our TPE-pHP-H2S NP donor which include (i) the excitation wavelength extended to >410 nm (ii) a large Stokes shift (iii) a low inner filter effect and (iv) real-time monitoring of H2S release by a simple fluorescent colour change. In vitro studies showed that the TPE-pHP-H2S NP donor presents excellent properties like real-time monitoring, photoregulated H2S release and biocompatibility.
Tetraphenylethylene-based thiazole solvent water fluorescent probe and preparation method thereof
-
Paragraph 0016; 0034; 0035; 0036, (2018/10/19)
The invention discloses a tetraphenylethylene-based thiazole solvent water fluorescent probe and a preparation method thereof, wherein the fluorescent probe is named TBTNO2, and has the chemical structural formula defined in the specification. The inventi
Synthesis and application of fluorescent reagent for selectively detecting cysteine based on aggregation-induced emission principle
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, (2017/07/20)
The invention discloses a fluorescent reagent for selectively detecting cysteine based on an aggregation-induced emission principle, a synthesis method and application thereof. Benzophenone is used as an initial raw material for synthesizing a target compound TPENNO2. The detection research of the target compound TPENNO2 to sulfydryl-contained amino acids (such as the cysteine, homocysteine and glutathione) is developed, and the target compound TPENNO2 is discovered to have the good sensitivity and the high selectivity to the cysteine, and the interference to the homocysteine and the glutathione is small. Compared with the prior art, the fluorescent reagent has the advantages of simple synthesis, easily obtained raw materials, high target compound fluorescence quantum yield, and strong photobleaching resistant capacity. The defect of traditional fluorochrome that cannot be detected in the high concentration is avoided, and the target compound TPENNO2 is successfully used for the fluorescence imaging of a sulfhydryl compound in cells. The target compound TPENNO2 has the large application prospect in the aspects of selectively detecting the cysteine and detecting the content of the sulfhydryl compound in the cells.
Fluorescence probe for detecting nitroreductase
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Paragraph 0010, (2017/09/02)
The invention discloses aggregation-induced emission (AIE) type fluorescence probe for detecting nitroreductase. The fluorescence probe is named as [2-(4-nitrophenyl)-1,1,2-triphenyl]ethylene, TPE-NO2 for short. The chemical structural formula of the fluorescence probe is represented by formula (I) (shown in the description). The fluorescence probe provided by the invention has response to nitroreductase in cells and can be used for detecting nitroreductase at an anoxic state of tumor cells by virtue of fluorescence imaging.
A new TICT and AIE-active tetraphenylethene-based Schiff base with reversible piezofluorochromism
Han, Fangfang,Zhang, Ran,Zhang, Zhaoming,Su, Jianguo,Ni, Zhonghai
, p. 68178 - 68184 (2016/08/02)
A new tetraphenylethene-based Schiff base N-5-nitrosalicylidene-4-tetraphenylethenylamine (NSTPE) was synthesized based on 4-tetraphenylethenylamine and 5-nitrosalicylaldehyde, and its structure was fully characterized by 1H NMR, 13C
