166273-19-4

Basic information

• Product Name: N-benzyl-3-(phenylselanyl)-pyrrolidin-2-one
• Synonyms: N-benzyl-3-(phenylselanyl)-pyrrolidin-2-one
• CAS NO: 166273-19-4
• Molecular Weight: 330.288
• Mol File: 166273-19-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-benzyl-3-(phenylselanyl)-pyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-3-(phenylselanyl)-pyrrolidin-2-one(166273-19-4)
• EPA Substance Registry System: N-benzyl-3-(phenylselanyl)-pyrrolidin-2-one(166273-19-4)

Safety Data

• Hazardous Substances Data: 166273-19-4(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 5291-77-0 1-benzyl-2-pyrrolidone 
• 34837-55-3 Phenylselenyl bromide 

Downstream Products

• 323204-69-9 1-benzyl-5-hydroxy-1,5-dihydro-2H-pyrrol-2-one 
• 64330-46-7 1-benzyl-1,5-dihydro-2H-pyrrole-2-one 

Relevant articles and documents

N-benzyl-5-hydroxy-3-pyrrolidin-2-one by hydrogen peroxide oxidation of N-benzyl-3-phenylseleno-2-pyrrolidinone

Using the known peroxide oxidation of N-benzyl-3-phenylseleno-2- pyrrolidinone with 30% hydrogen peroxide at -5°C after 3.5 h, we prepared the expected N-benzyl-3-pyrrolin-2-one. However, reaction with 30% hydrogen peroxide for 12 h (-5°C→ambient) gave the unexpected product N-benzyl-5-hydroxy-3-pyrrolidin-2-one in 84% isolated yield. This procedure is a new synthetic route to N-benzyl-5-hydroxy-3-pyrrolidin-2-one. Copyright Taylor & Francis Group, LLC.

Preparation and epoxidation of conjugated lactams: Influence of ring size on epoxidation

α,β-Epoxy-lactams can be prepared from conjugated lactams by treatment with m-chloroperoxybenzoic acid. Good yields are obtained, however, only with 2-pyrrolidinone derivatives. The yield of epoxy-lactam diminishes dramatically as the size of the lactam ring increases.