166274-91-5

Upstream product

• 73-32-5 L-isoleucine 
• 2577-46-0 L-isoleucine methyl ester 
• 100-58-3 phenylmagnesium bromide 

Downstream Products

• 1628720-48-8 2,6-bis((2S,4S)-4-((S)-sec-butyl)-5,5-diphenyloxazolidin-2-yl)pyridine 

Relevant academic research and scientific papers

Chiral Bis(oxazolidine)pyridine-copper-catalyzed enantioselective friedel-crafts alkylation of indoles with nitroalkenes

Catalytic asymmetric Friedel-Crafts reaction of indoles with nitroalkenes was catalyzed by the stereochemically tunable bis(oxazolidine)pyridine (PyBodine)-Cu(OTf)2 complex. Using the PyBodine(Val)-Cu(OTf) 2 catalyst gave the Friedel-Crafts ?adducts with highly enantioselective manner. For the 1,4-bis[(E)-2-nitrovinyl]benzene, the reaction proceeded in a meso-trick manner to give the chiral double Friedel-Crafts adduct with 97% enantiomeric excess. Georg Thieme Verlag Stuttgart New York.