166281-37-4 Usage
Uses
Used in Pharmaceutical Industry:
2-Bromo-4,5-difluorophenol is used as an intermediate compound for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, particularly those targeting specific biological pathways or receptors.
Used in Chemical Synthesis:
In the field of chemical synthesis, 2-Bromo-4,5-difluorophenol is utilized as a building block for creating more complex organic molecules. Its reactivity and structural features make it a valuable precursor in the synthesis of various specialty chemicals, including those with potential applications in materials science, agrochemicals, and other industrial sectors.
Used in Material Science:
2-Bromo-4,5-difluorophenol is used as a component in the development of advanced materials, such as polymers and coatings, due to its ability to undergo specific chemical reactions. Its incorporation into these materials can enhance their properties, such as thermal stability, chemical resistance, or mechanical strength.
Used in Research and Development:
As a versatile organic compound, 2-Bromo-4,5-difluorophenol is employed in research and development laboratories for studying its properties and potential applications. It serves as a model compound for understanding the behavior of similar molecules and for testing new synthetic methods or reaction conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 166281-37-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,2,8 and 1 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 166281-37:
(8*1)+(7*6)+(6*6)+(5*2)+(4*8)+(3*1)+(2*3)+(1*7)=144
144 % 10 = 4
So 166281-37-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H4BF6.K/c9-7(10,11)5-1-3-6(4-2-5)8(12,13)14;/h1-4H;/q-1;+1
166281-37-4Relevant academic research and scientific papers
Construction of Phenanthrenes and Chrysenes from β-Bromovinylarenes via Aryne Diels-Alder Reaction/Aromatization
Singh, Vikram,Verma, Ram Subhawan,Khatana, Anil K.,Tiwari, Bhoopendra
supporting information, p. 14161 - 14167 (2019/10/28)
A highly efficient transition-metal-free general method for the synthesis of polycyclic aromatic hydrocarbons like phenanthrenes and chrysenes (and tetraphene) from β-bromovinylarenes and arynes has been developed. The reactions proceed via an aryne Diels-Alder (ADA) reaction, followed by a facile aromatization. This is the first report on direct construction of chrysenes (and tetraphene) using the ADA approach. Unlike the literature method which is limited to only 9/10-substituted derivatives, this method gives access to a wide variety of functionalized phenanthrenes.
Copper-Catalyzed Selective ortho-C-H/N-H Annulation of Benzamides with Arynes: Synthesis of Phenanthridinone Alkaloids
Zhang, Ting-Yu,Lin, Jun-Bing,Li, Quan-Zhe,Kang, Jun-Chen,Pan, Jin-Long,Hou, Si-Hua,Chen, Chao,Zhang, Shu-Yu
supporting information, p. 1764 - 1767 (2017/04/11)
An efficient and convenient copper-catalyzed method has been developed to achieve direct ortho-C-H/N-H annulation to synthesize phenanthridinones with arynes. This method highlights an emerging strategy to transform inert C-H bonds into versatile functional groups in organic synthesis and provides a new way to synthesize phenanthridinone alkaloids efficiently.
