2713-33-9

Basic information

• Product Name: 3,4-Difluorophenol
• Synonyms: 3,4-DIFLUOROPHENOL;3,4-Difluoropheno;3,4-Difluorophenol,98%;3,4-Difluorophenol99%;3,4-2-fluorophenol;3,4-Difluorophenol, 99% 5GR;3,4-Difluorophenol, 97+%;3, 4 - two fluorine phenol
• CAS NO: 2713-33-9
• Molecular Formula: C₆H₄F₂O
• Molecular Weight: 130.09
• EINECS: 424-300-1
• Product Categories: Fluorobenzene Series;Aromatic Phenols;Fluorobenzene;Phenol&Thiophenol&Mercaptan;Fluorine Compounds;Phenols;Fluorophenols;Organic Building Blocks;Oxygen Compounds;Aryl Fluorinated Building Blocks;Building Blocks;C6;C6 to C8;Chemical Synthesis;Fluorinated Building Blocks;Organic Building Blocks;Organic Fluorinated Building Blocks;Other Fluorinated Organic Building Blocks;Oxygen Compounds
• Mol File: 2713-33-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 34-38 °C(lit.)
• Boiling Point: 85 °C20 mm Hg(lit.)
• Flash Point: 136 °F
• Appearance: white to light yellow crystals
• Density: 1.2483 (estimate)
• Vapor Pressure: 0.53mmHg at 25°C
• Refractive Index: 1.495
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 8.98±0.18(Predicted)
• BRN: 2081085
• CAS DataBase Reference: 3,4-Difluorophenol(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Difluorophenol(2713-33-9)
• EPA Substance Registry System: 3,4-Difluorophenol(2713-33-9)

Safety Data

• Hazard Codes: Xi,F,C,Xn
• Statements: 36/37/38-34-20/21/22-11-21/22
• Safety Statements: 26-36-45-36/37/39-16
• RIDADR: UN 1325 4.1/PG 2
• WGK Germany: 3
• HazardClass: 4.1
• PackingGroup: II
• Hazardous Substances Data: 2713-33-9(Hazardous Substances Data)

Usage

Chemical Properties

white to yellowish crystalline low melting solid

Uses

Intermediates of Liquid Crystals

General Description

Transformation of 3,4-difluorophenol by Penicillium frequentans strain Bi 7/2, using phenol as a sole source of carbon and energy, has been reported.

InChI:InChI=1/C6H4F2O/c7-5-2-1-4(9)3-6(5)8/h1-3,9H

Upstream product

• 3863-11-4 3,4-difluoroaniline 
• 367-11-3 ortho-difluorobenzene 
• 34036-07-2 3,4 difluorobenzaldehyde 
• 369-34-6 3,4-difluoronitrobenzene 
• 1188330-33-7 C₁₄H₁₅F₄NO₆ 
• 1188330-43-9 C₁₄H₁₄F₅NO₆ 
• 1200828-99-4 C₁₇H₂₃F₂NO₆ 
• 1188330-19-9 C₁₄H₁₇F₂NO₆ 
• 1188330-26-8 C₁₄H₁₆F₃NO₆ 
• 168267-41-2 (3,4-difluorophenyl)boronic acid 

Downstream Products

• 170876-51-4 1-(3,4-difluorophenoxy)-2,3-epoxypropane 
• 115144-40-6 1,2-difluoro-4-methoxy-benzene 
• 708276-49-7 2-(3,4-difluorophenoxy)-1-(4-methylsulfanylphenyl)ethanone 
• 749230-22-6 1,2-difluoro-4-(methoxymethoxy)benzene 
• 187543-87-9 2,3-difluoro-6-methoxybenzaldehyde 
• 167684-02-8 6-ethoxy-2,3-difluoro-benzaldehyde 
• 910394-72-8 2,3-difluoro-6-methoxyphenethylamine 
• 1027179-28-7 2,3-difluoro-6-ethoxyphenethylamine 
• 1026343-70-3 1-Ethoxy-3,4-difluoro-2-((E)-2-nitro-vinyl)-benzene 
• 181305-41-9 1-(5-Bromo-pyridin-2-yl)-3-[2-(2,3-difluoro-6-methoxy-phenyl)-ethyl]-thiourea 
• 181305-40-8 1-(5-Bromo-pyridin-2-yl)-3-[2-(6-ethoxy-2,3-difluoro-phenyl)-ethyl]-thiourea 
• 199586-66-8 3,4-difluorophenyl acetate 
• 262287-83-2 4-acetylthio-1-[4-(3', 4'-difluorophenoxy)benzyl]pyrrolidin-2-one 
• 426843-36-9 4-(2-bromoethoxy)-1,2-difluorobenzene 

Relevant articles and documents

Cellulose as recyclable organocatalyst for ipso-hydroxylation of arylboronic acids

Cellulose catalyzed oxidative hydroxylation of aryl and hetero-arylboronic acids to the corresponding phenols under metal and base free strategy has been demonstrated. The sustainable ipso-hydroxylation takes place using hydrogen peroxide as an oxidant in water under mild condition in shorter period of time. Interestingly, easy recovery and reusability of heterogeneous catalyst without significant loss in catalytic yield makes the protocol environmentally benign.

Enzymatic Baeyer-Villiger oxidation of benzaldehydes

The selectivity of the chemical Baeyer-Villiger oxidation of benzaldehydes depends on steric and electronic factors, the type of oxidizing agent and the reaction conditions. Here we report on the enzymatic Baeyer-Villiger oxidation of fluorobenzaldehydes

SYNTHESIS AND SOME PROPERTIES OF 3,4-DIFLUOROPHENYL TRANS-4 prime -SUBSTITUTED CYCLOHEXANE-1 prime -CARBOXYLATES.

A new series of 3,4-difluorophenyl trans-4 prime -substituted cyclohexane-1 prime -carboxylates was synthesized in order to achieve a nematic compound of positive dielectric anisotropy and low viscosity. The effect of fluoro substituents on mesomorphic and physical properties was established by comparing these compounds with other fluorinated nematic compounds.