16631-25-7

Usage

Uses

Used in Organic Synthesis:
Methyl 2-bromotetradecanoate is used as a synthetic intermediate for the production of various organic compounds. Its application in this field is due to its reactivity and ability to undergo a range of chemical reactions, making it a versatile building block for the synthesis of complex molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Methyl 2-bromotetradecanoate is used as a key component in the development of new drugs. Its unique chemical structure allows it to be incorporated into the design of novel therapeutic agents, potentially leading to the discovery of new medications with improved efficacy and reduced side effects.
Used in Chemical Research:
Methyl 2-bromotetradecanoate is also utilized in chemical research as a model compound for studying various reaction mechanisms and exploring new synthetic routes. Its use in this context helps researchers gain a deeper understanding of organic chemistry and develop innovative strategies for the synthesis of complex molecules.

InChI:InChI=1/C15H29BrO2/c1-3-4-5-6-7-8-9-10-11-12-13-14(16)15(17)18-2/h14H,3-13H2,1-2H3

Upstream product

• 67-56-1 methanol 
• 10520-81-7 2-bromomyristic acid 
• 112-64-1 tetradecanoyl chloride 

Relevant academic research and scientific papers

Synthesis and antifungal activities of myristic acid analogs

Myristic acid analogs that are putative inhibitors of N-myristoyl transferase were tested in vitro for activity against yeasts (Saccharomyces cerevisiae, Candida albicans, Cryptococcus neoformans) and filamentous fungi (Aspergillus niger). Several (±)-2-halotetradecanoic acids including (±)-2-bromotetradecanoic acid (14c) exhibited potent activity against C. albicans (MIC = 39 μM), C. neoformans (MIC = 20 μM), S. cerevisiae (MIC = 10 μM), and A. niger (MIC 42 μM) in RPMI 1640 media. Improved synthetic methods have been developed for the synthesis of 12-fluorododecanoic acid (12a) and 12-chlorododecanoic acid (12c). Three novel fatty acids, 12-chloro-4-oxadodecanoic acid (8a), 12-phenoxydodecanoic acid (12i), and 11-(4-iodophenoxy)-undecanoic acid (13d) were also synthesized and tested.

Synthesis and Structure Elucidation of γ-Aminobutyric Acid Conjugates with Lipidic Acids, Lipidic Amino Acids and Lipidic Peptides

A series of γ-aminobutyric acid esters of lipidic acids, lipidic peptides and γ-aminobutyric acid amides of lipidic α-amino acids and oligomers were synthesised.The GABA conjugates with ester linkages (6j-r) were prepared by coupling the lipidic acids and peptide conjugates to the carboxyl terminus of GABA.Two types of GABA conjugates linked by amide bonds were synthesised.This class included compounds 5d-f in which the amino group of the lipidic amino acid is condensed with the carboxyl function of GABA and compounds 7a-b with the carboxyl terminus of the α-amino acid coupled to the amino group of GABA.The lipidic amino acid peptide oligomers were varied from 1-3 units, and the alkyl side chains ranged from 5-17 carbon atoms in length in order to impart different lipophilicities to the GABA molecule conjugates. Key Words: Amino acids, fatty / Peptides, lipidic / Lipophilic GABA conjugates / Drug delivery