166337-41-3

Basic information

• Product Name: Benzenepropanamide, N-methoxy-N-methyl-b-phenyl-
• CAS NO: 166337-41-3
• Molecular Formula: C17H19NO2
• Molecular Weight: 269.343
• Mol File: 166337-41-3.mol

Chemical Properties

• CAS DataBase Reference: Benzenepropanamide, N-methoxy-N-methyl-b-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanamide, N-methoxy-N-methyl-b-phenyl-(166337-41-3)
• EPA Substance Registry System: Benzenepropanamide, N-methoxy-N-methyl-b-phenyl-(166337-41-3)

Safety Data

• Hazardous Substances Data: 166337-41-3(Hazardous Substances Data)

Upstream product

• 606-83-7 3,3-Diphenylpropionic acid 
• 6638-79-5 N,O-dimethylhydroxylamine*hydrochloride 
• 37089-77-3 3,3-diphenylpropanoyl chloride 

Downstream Products

• 1443367-54-1 3-(naphthalen-2-yl)-5,5-diphenyl-4,5-dihydroisoxazole 
• 1443367-78-9 1-(naphthalen-2-yl)-3,3-diphenylpropan-1-one oxime 
• 1443368-20-4 1-(naphthalen-2-yl)-3,3-diphenylpropan-1-one 
• 876404-32-9 2-tert-butoxycarbonylamino-3-[2-(3,3-diphenyl-propionyl)-1-(2-methoxy-ethoxymethyl)-1H-imidazol-4-yl]-3-hydroxy-propionic acid methyl ester 
• 876404-49-8 {2-[2-(3,3-diphenyl-propionyl)-1-(2-methoxy-ethoxymethyl)-1H-imidazol-4-yl]-ethyl}-carbamic acid benzyl ester 
• 876404-79-4 3-[2-(3,3-diphenyl-propionyl)-1-(2-methoxy-ethoxymethyl)-1H-imidazol-4-yl]-propionic acid 
• 876404-39-6 3-[2-(3,3-diphenyl-propionyl)-1-(2-methoxy-ethoxymethyl)-1H-imidazol-4-yl]-propionic acid methyl ester 
• 876404-40-9 1-[4-(2-amino-ethyl)-1-(2-methoxy-ethoxymethyl)-1H-imidazol-2-yl]-3,3-diphenyl-propan-1-one 
• 876404-44-3 1-[4-[3-(tert-butyl-dimethyl-silanyloxy)-propenyl]-1-(2-methoxy-ethoxymethyl)-1H-imidazol-2-yl]-3,3-diphenyl-propan-1-one 

Relevant articles and documents

Weinreb Amide, Ketone and Amine as Potential and Competitive Secondary Molecular Stations for Dibenzo-[24]Crown-8 in [2]Rotaxane Molecular Shuttles

This paper reports the synthesis and study of new pH-sensitive DB24C8-based [2]rotaxane molecular shuttles that contain within their axle four potential sites of interaction for the DB24C8: ammonium, amine, Weinreb amide, and ketone. In the protonated state, the DB24C8 lay around the best ammonium site. After either deprotonation or deprotonation-then-carbamoylation of the ammonium, different localizations of the DB24C8 were seen, depending on both the number and nature of the secondary stations and steric restriction. Unexpectedly, the results indicated that the Weinreb amide was not a proper secondary molecular station for the DB24C8. Nevertheless, through its methoxy side chain, it slowed down the shuttling of the macrocycle along the threaded axle, thereby partitioning the [2]rotaxane into two translational isomers on the NMR timescale. The ketone was successfully used as a secondary molecular station, and its weak affinity for the DB24C8 was similar to that of a secondary amine.

Halide-Accelerated Acyl Fluoride Formation Using Sulfuryl Fluoride

Herein, we report a new one-pot sequential method for SO2F2-mediated nucleophilic acyl substitution reactions starting from carboxylic acids. A mechanistic study revealed that SO2F2-mediated acid activation proceeds via the anhydride, which is then converted to the corresponding acyl fluoride. Tetrabutylammonium chloride or bromide accelerate the formation of acyl fluoride. Optimized halide-accelerated conditions were used to synthesize acyl fluorides in 30-80percent yields, and esters, amides, and thioesters in 72-96percent yields without reoptimization for each nucleophile.

TEMPO-mediated aliphatic C-H Oxidation with Oximes and hydrazones

A method for aliphatic C-H bond oxidation of oximes and hydrazones mediated by 2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPO) has been developed, which enables the concise assembly of substituted isoxazole and pyrazole skeletons.

4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL[B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS

The present invention relates to compounds of formula I which are 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl[b]pyran-2-ones useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus. STR1 Wherein R 10 and R 20 taken together are: STR2