166395-00-2Relevant academic research and scientific papers
Phosphonic diester derivatives
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, (2008/06/13)
The present invention provides a phosphonic diester derivative of the following general formula (1): STR1 wherein A represents an oxygen atom or a sulfur atom; R1, R2, R9 and R10 are the same or different and th
Synthesis and hypolipidemic activities of novel 2-[4-[(diethoxyphosphoryl)methyl]phenyl]quinazolines and 4(3H)-quinazolinones
Kurogi, Yasuhisa,Inoue, Yasuhide,Tsutsumi, Kazuhiko,Nakamura, Shizuo,Nagao, Kazushi,Yoshitsugu, Hiroki,Tsuda, Yoshihiko
, p. 1433 - 1437 (2007/10/03)
The novel compound NO-1886, 4-[(diethoxyphosphoryl)methyl]-N-(4-bromo-2-cyanophenyl)-benzamide, is a hypolipidemic agent, which appears to increase lipoprotein lipase activity in rats. Various analogs of NO-1886 were synthesized to study the structure-act
Method for treating hyperlipidemia
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, (2008/06/13)
A pharmaceutical composition for treating hyperlipidemia containing, as the active ingredient, at least one carboxamide compounds represented by the formula (1) which possess excellent activities in lowering serum lipid, as well as having low toxicity with high safety. Said carboxamide compounds represented by the formula (1) are known compounds developed by the present inventors, but the pharmacological activities for treating hyperlipidemia have not been found yet.
