1664-31-9Relevant articles and documents
Comparative study of dG affinity vs. DNA methylation modulating properties of side chain derivatives of procainamide: Insight into its DNA hypomethylating effect
Gawade,Chakravarty,Debgupta,Sangtani,Narwade,Gonnade,Puranik,Deobagkar
, p. 5350 - 5358 (2016/02/05)
Procainamide derivatives have been synthesized to investigate the role of side chains in modulating the DNA methylation level in cancer cells and gain insight into its mechanism of action. The synthesized derivatives comprised of flexible (dimethyl), cons
Design, synthesis, and biological evaluation of novel water-soluble N-mustards as potential anticancer agents
Kapuriya, Naval,Kakadiya, Rajesh,Dong, Huajin,Kumar, Amit,Lee, Pei-Chih,Zhang, Xiuguo,Chou, Ting-Chao,Lee, Te-Chang,Chen, Ching-Huang,Lam, King,Marvania, Bhavin,Shah, Anamik,Su, Tsann-Long
experimental part, p. 471 - 485 (2011/02/27)
A series of novel water-soluble N-mustard-benzene conjugates bearing a urea linker were synthesized. The benzene moiety contains various hydrophilic side chains are linked to the meta- or para-position of the urea linker via a carboxamide or an ether link