1664-34-2

Usage

Uses

Used in Pharmaceutical Industry:
1-Aminocyclohexanecarboxylic acid ethyl ester is used as a key intermediate in the synthesis of pharmaceutical compounds for its versatility in chemical reactions and potential biological activity. Its ethyl ester form enhances its solubility in organic solvents, facilitating its use in a wide range of applications within drug development and therapeutic agent creation.
Used in Organic Synthesis:
In the field of organic synthesis, 1-Aminocyclohexanecarboxylic acid ethyl ester serves as a versatile building block for the creation of various organic compounds. Its reactivity and functional groups allow for the formation of diverse chemical structures, contributing to the advancement of organic chemistry.
Used in Medicinal Chemistry:
1-Aminocyclohexanecarboxylic acid ethyl ester is utilized in medicinal chemistry for the development of new drugs and therapeutic agents. Its potential biological activity and chemical properties make it a promising candidate for the creation of novel pharmaceuticals aimed at treating various diseases and conditions.

InChI:InChI=1/C9H17NO2/c1-2-12-8(11)9(10)6-4-3-5-7-9/h2-7,10H2,1H3

Upstream product

• 64-17-5 ethanol 
• 2756-85-6 1-aminocyclohexane carboxylic acid 
• 111-24-0 1,5-dibromo-pentane 
• 34893-92-0 3,4-dichlorophenyl isocyanate 
• 1130-21-8 ethyl 1-cyanocyclohexane-1-carboxylate 

Downstream Products

• 1124-96-5 2-(1-hydroxycyclohexyl)propan-2-ol 
• 40702-53-2 1-(1-amino-cyclohexyl)-ethanone 
• 858835-42-4 1-(1-amino-cyclohexyl)-propan-1-one 
• 15015-46-0 1--1-cyclohexanol 
• 4313-56-8 (1-aminocyclohexyl)methanol 
• 13908-21-9 1-[3-(2-Chloro-ethyl)-ureido]-cyclohexanecarboxylic acid ethyl ester 
• 115572-36-6 1-[(S)-2-((S)-2-Benzyloxycarbonylamino-propionylamino)-propionylamino]-cyclohexanecarboxylic acid ethyl ester 
• 75230-16-9 1-[(Z)-2,3-Dibromo-4,4-bis-(4-ethyl-phenyl)-but-2-enoylamino]-cyclohexanecarboxylic acid ethyl ester 
• 115572-53-7 1-[(S)-2-((S)-2-Amino-propionylamino)-propionylamino]-cyclohexanecarboxylic acid ethyl ester 
• 13991-74-7 1-({[(2-chloroethyl)nitrosoamino]carbonyl}amino)-cyclohexanecarboxylic acid, ethyl ester 
• 326500-10-1 1-(dibenzofuran-3-sulfonylamino)cyclohexanecarboxylic acid ethyl ester 
• 158721-27-8 ethyl 1-(2-ethoxycarbonylethylamino)cyclohexanecarboxylate 
• 89732-44-5 ethyl 1-(3-ethoxycarbonylpropylamino)cyclohexanecarboxylate 

Relevant academic research and scientific papers

Synthesis and use of achiral oxazolidine-2-thiones in selective preparation of trans 2,5-disubstituted tetrahydrofurans

The use of achiral N-acetyloxazolidine-2-thiones in the C-glycosylation of lactol acetates has allowed us to prepare with high diastereoselectivity the expected trans 2,5-disubstituted tetrahydrofurans. A study based on the role of the steric hindrance of the N-acetyloxazolidine-2-thiones is reported. Wiley-VCH Verlag GmbH & Co. KGaA, 2009.

Substituted 2, 4-imidazolidinedione compounds as pharmaceutical active ingredients

A substituted 2,4-imidazolidinedione compound corresponding to the formula I STR1 a process for production thereof and the use of these compounds in a pharmaceutical preparation are described. Substituents R1, R2, R3 and R4 have the same meaning as defined in the specification.

Therapeutic agents

Compounds of formula I STR1 and pharmaceutically acceptable salts thereof in which m is an integer from 1 to 3; n is an integer from 2 to 6; R1 is phenyl optionally substituted by one or more substituents selected from halo, hydroxy, alkoxy, alkanoyl, alkyl, halogenated alkyl, alkylthio, alkylsulphinyl, alkylsulphonyl, cyano, nitro, optionally substituted amino, optionally substituted sulphamoyl, optionally substituted carbamoyl or phenyl, or R1 is naphthyl; R2 is H, alkyl or phenyl; R3 is H, alkyl, alkenyl or alkoxyalkyl; R4 is H or hydroxy; and R5 is H or together with R4 represents a bond; have utility in the treatment of obesity and affective disorders such as depression and anxiety.

A simple method for the synthesis of cyclic α-amino acids

The benzylidene derivative of glycine ethyl ester was alkylated with various electrophiles to synthesize cyclic α-amino acids bearing aromatic and aliphatic side chains.

Herbicidal hydantoins

Novel cycloalkane-5=-spiro-hydantoins of formula STR1 wherein A is selected from the group consisting of STR2 and the remaining substituents are defined below having strong, selective herbicidal activity and novel intermediates and a process for their pre

A FACILE PROCEDURE FOR THE PREPARATION OF ALICYCLIC α-AMINO ACIDS

A convenient method for the preparation of alicyclic α-amino acids is described which utilizes ethyl isocyanoacetate and the appropriate dibromo-substituted aliphatic alkylating agent.

Substituted 1-azaspiro[4,5]decanes and their analgesic compositions

This invention relates to substituted 1-azaspiro[4.5] decanes and 1-azaspiro[5.5]undecanes of the formula STR1 wherein R1 is hydrogen, --CO2 R4, R4 ; R2 is hydrogen, STR2 R3 is hydrogen, STR3 R4 is alkyl of 1 to 4 carbon atoms; R5 is alkyl of 1 to 8 carbon atoms; X is halogen, alkyl of 1 to 4 carbon atoms, alkoxy of 1 to 4 carbon atoms, CF3, and OH; m is an integer of 0, 1 or 2; and n is an integer of 1 or 2.