16645-01-5Relevant academic research and scientific papers
Simple Stereospecific Syntheses of (E)-1-Chloro(or Bromo)alk-1-enes from Alk-1-ynes via Hydroboration
Masuda, Yuzuru,Hoshi, Masayuki,Arase, Akira
, p. 2723 - 2726 (2007/10/02)
Stereochemically pure (E)-1-chloro(or bromo)alk-1-enes were obtained in sufficiently good yields from alk-1-ynes via hydroboration with dialkylborane followed by reactions with facile reagents; corresponding copper(II) halides, in the presence of a small
Vinylic Organoboranes. 13. A Convenient Stereospecific Synthesis of (Z)-1-Halo-1-alkenes from 1-Alkynes via (E)-1-Alkenylborane Derivatives with Halogens
Brown, Herbert C.,Subrahmanyam, Chitti,Hamaoka, Tsutomu,Ravindran, Nair,Bowman, Donald H.,et al.
, p. 6068 - 6075 (2007/10/02)
The reaction of (E)-1-alkenylborane derivatives with bromine under various conditions was investigated, and a simple stereospecific synthesis of (Z)-1-bromo-1-alkenes has been developed.Addition of bromine to (E)-1-alkenyldisiamylborane, derived from the
Palladium-Catalyzed Synthesis of 2,4-Dienoic Acid Derivatives from Vinylic Halides
Kim, Jin-Il,Patel, Babu A.,Heck, Richard F.
, p. 1067 - 1073 (2007/10/02)
A wide variety of vinylic bromides and iodides have been coupled with acrylic, methacrylic, crotonic, and maleic esters and in some cases with the free acids, nitriles, and amides.In general, good yields of the 2,4-dienoic acid derivatives were obtained.The stereochemistry of the products was determined and the factors influencing the stereoselec-tivity of the reaction were studied.
