16651-07-3

Upstream product

• 123-73-9 trans-Crotonaldehyde 
• 13466-40-5 (2E, 4E)-5-phenylpenta-2,4-dienal 
• 100-52-7 benzaldehyde 
• 255387-11-2 1-Bromo-6-methoxyhexa-1,3,5-triene 
• 255387-05-4 6,6-diethoxy-1-bromohexa-3,5-diene 
• 253156-54-6 2-[1-(1,3-Diox-4-en-6-yl)-2-propenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 328385-44-0 (2E,4E)-7-Hydroxy-7-phenylhepta-2,4-dienal 
• 32410-52-9 (2E,4E,6E)-7-phenylhepta-2,4,6-trienal 
• 328385-57-5 (2E,4E,8E,10E)-7,13-Dihydroxy-13-phenyltrideca-2,4,8,10-tetraenal 

Relevant academic research and scientific papers

Syntheses of three new lithio hexavinylogation reagents

Syntheses of new lithio hexavinylogation reagents are described starting either from ω-bromo polyenacetal, ω-bromo polyenol ether or ω-bromo non conjugated aldehyde. The reactivity of the lithio reagents has been tested by condensation with benzaldehyde;

Efficient homologation of aldehydes to 2,4,6-alkatrienals by means of an α-(1,3-dioxenylallyl)boronate

The α-dioxenyl-allylboronate 4 allows the direct conversion of aldehydes into the 7-hydroxy-2,4-dienals (6). The latter compounds can be dehydrated to 2,4,6-alkatrienals 7 by means of the Burgess reagent or methanesulfonyl anhydride/Hunig Base.