166524-65-8 Usage
Uses
Used in Pharmaceutical Industry:
2-Ethoxy-4,6-difluoropyrimidine is used as a chemical intermediate for the synthesis of various pharmaceutical compounds, particularly in the development of antiviral and anticancer drugs. Its unique structure and properties contribute to the creation of effective therapeutic agents.
Used in Agricultural Industry:
In the agricultural sector, 2-Ethoxy-4,6-difluoropyrimidine is utilized in the development of pesticides and herbicides. Its chemical properties allow for the formulation of products that can effectively control and manage pests and weeds, thereby enhancing crop protection and yield.
2-ETHOXY-4,6-DIFLUOROPYRIMIDINE's versatility and potential applications make it a valuable asset for researchers and chemists working in both the medical and agricultural fields, as they continue to explore and innovate new uses for this promising chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 166524-65-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,5,2 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 166524-65:
(8*1)+(7*6)+(6*6)+(5*5)+(4*2)+(3*4)+(2*6)+(1*5)=148
148 % 10 = 8
So 166524-65-8 is a valid CAS Registry Number.
InChI:InChI=1/C6H6F2N2O/c1-2-11-6-9-4(7)3-5(8)10-6/h3H,2H2,1H3
166524-65-8Relevant academic research and scientific papers
Production process of 2-ethoxy-4, 6-difluoropyrimidine
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Paragraph 0037-0043, (2020/07/15)
The invention discloses a synthesis method of 2-ethoxy-4, 6-difluoropyrimidine, which comprises the following steps: (1) reacting urea with diethyl sulfate in an organic solvent at 60-120 DEG C to prepare an intermediate I; (2) synthesizing an intermediate II from the intermediate I and diethyl malonate; (3) performing chlorination on the intermediate II to obtain an intermediate III; and (4) reacting the intermediate III with a fluorinated reagent at 80-120 DEG C for 6 hours, and performing separation and purification to obtain the target product 2-ethoxy-4, 6-difluoropyrimidine, which has astructure described in the specification. The initial raw material urea adopted by the invention is low in price and easy to obtain, the production cost is low, the reaction process is simple and reasonable, the production safety is high, the operation is simple, and the method is suitable for industrial large-scale production.
2-alkoxy-4-hydrazinopyrimidine compounds
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, (2008/06/13)
5-Alkoxy-1,2,4-triazolo[4,3-c]pyrimidine-3(2H)-thione compounds, such as 5-ethoxy-8-fluoro-1,2,4-triazolo[4,3-c]pyrimidine-3(2H)-thione, were prepared by cyclization of 2-alkoxy-4-hydrazinopyrimidine compounds, such as 2-ethoxy-5-fluoro-4-hydrazinopyrimid