1665276-15-2

Upstream product

• 16473-35-1 4-(hydroxymethyl)benzyl chloride 
• 142-08-5 2-hydroxypyridin 
• 1564668-60-5 1-{[4-(hydroxymethyl)phenyl]methyl}-1,2-dihydropyridin-2-one 
• 1618648-07-9 1-(4-azidomethylbenzyl)-1H-pyridin-2-one 
• 1618648-08-0 1-[4-(2-oxo-2H-pyridin-1-ylmethyl)benzyl]-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester 
• 1618648-09-1 1-[4-(2-oxo-2H-pyridin-1-ylmethyl)benzyl]-1H-[1,2,3]triazole-4-carboxylic acid 
• 1618648-10-4 {4-[({1-[4-(2-oxo-2H-pyridin-1-ylmethyl)benzyl]-1H-[1,2,3]triazole-4-carbonyl}amino)-5-methyl]benzyl}carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

BENZYLAMINE DERIVATIVES

The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in therapy (for example in the treatment or prevention of a disease or condition in which plasma kallikrein activity is implicated); and methods of treating patients with such compounds; wherein R1 to R3, R5 to R9, A, P, V, W, X, Y and Z are as defined herein.