166537-41-3Relevant articles and documents
Synthesis and Conformation of Hexahydro-isoquinobenzazepines of the B-Homoberbine Type
Meise, Werner,Zlotos, Darius,Jansen, Martin,Zoche, Nicola
, p. 567 - 574 (2007/10/02)
The two-step synthesis of the hexahydro-isoquinobenzazepines ("B-homoberbines") 4b-e is described.The main and some further products of the Bischler-Napieralski reaction of hydroxyamide 3c were isolated and identified.The conformation of the B-homoberbines was investigated by X-ray analysis, spectroscopic methods and dehydrogenation with mercury(II) acetate. - Key Words: Isoquinobenzazepines / B-Homoberbines / Bischler-Napieralski reaction / Calculations, MMX force-field