14773-42-3

Basic information

• Product Name: 3-(3,4-DIMETHOXY-PHENYL)-PROPYLAMINE
• Synonyms: 3-(3,4-DIMETHOXY-PHENYL)-PROPYLAMINE;AKOS BB-3062;3,4-DiMethoxy-benzenepropanaMine;3-(3,4-DiMethoxy-phenyl)-propylaMine hydrochloride
• CAS NO: 14773-42-3
• Molecular Formula: C₁₁H₁₇NO₂
• Molecular Weight: 195.26
• Mol File: 14773-42-3.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 296.2°C at 760 mmHg
• Flash Point: 144.8°C
• Appearance: /
• Density: 1.025g/cm³
• Vapor Pressure: 0.00146mmHg at 25°C
• Refractive Index: 1.513
• PKA: 10.20±0.10(Predicted)
• CAS DataBase Reference: 3-(3,4-DIMETHOXY-PHENYL)-PROPYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-DIMETHOXY-PHENYL)-PROPYLAMINE(14773-42-3)
• EPA Substance Registry System: 3-(3,4-DIMETHOXY-PHENYL)-PROPYLAMINE(14773-42-3)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 14773-42-3(Hazardous Substances Data)

Usage

General Description

3-(3,4-Dimethoxy-phenyl)-propylamine, also known as DM-PPA, is a chemical compound with the molecular formula C12H19NO2. It is a derivative of phenethylamine and acts as a selective serotonin releasing agent. DM-PPA is often used in research settings as a tool to study the effects of serotonin release on the central nervous system. It has also been investigated for its potential therapeutic applications, particularly in the treatment of mood disorders and depression. Additionally, DM-PPA has been studied for its role in the regulation of appetite and weight management. Overall, this chemical compound has shown promise in various research areas and may have potential for future clinical use.

InChI:InChI=1/C11H17NO2/c1-13-10-6-5-9(4-3-7-12)8-11(10)14-2/h5-6,8H,3-4,7,12H2,1-2H3

Upstream product

• 6443-72-7 3-(3,4-dimethoxyphenyl)acrylonitrile 
• 107-10-8 propylamine 
• 5460-32-2 1-iodo-3,4-dimethoxybenzene 
• 27798-73-8 methyl 3-(3,4-dimethoxyphenyl)propionate 
• 2107-70-2 3,4-methoxycinnamic acid 
• 86213-20-9 2-cyano-3-(3,4-dimethoxyphenyl)acrylic acid 
• 49621-56-9 3-(3,4-dimethoxyphenyl)propanenitrile 
• 130973-10-3 (2E)-3-(3,4-dimethoxyphenyl)-2-propenamide 
• 14773-41-2 3-(3,4-dimethoxyphenyl)propionic acid amide 
• 55502-61-9 2-cyano-3-(3,4-dimethoxyphenyl)propionic acid 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 166537-41-3 N-<3-(3,4-Dimethoxyphenyl)propyl><2-(hydroxymethyl)phenyl>acetamid 
• 113193-85-4 N-acetyl-3-(3',4'-dimethoxyphenyl)-propylamine 
• 860436-54-0 7,8-dimethoxy-2,3,4,5-tetrahydro-1H-2-benzazepine hydrochloride 
• 1454706-71-8 C₂₀H₂₈N₂O₆ 
• 36209-75-3 N-[3-(3,4-dimethoxy-phenyl)-propyl]-phthalimide 
• 129881-33-0 N-(cyclohex-1-enyl)-N-<3-(3,4-dimethoxyphenyl)propyl>-α-(methylsulfinyl)acetamide 
• 129881-34-1 1,4,5,6,7,7a-hexahydro-1-<3-(3,4-dimethoxyphenyl)propyl>-3-methylthio-2H-indol-2-one 
• 108010-36-2 2-<3-(3,4-Dimethoxyphenyl)propyl>-3,4-dihydroisochinolin-1(2H)-on 
• 116467-34-6 N-<3-(3,4-Dimethoxyphenyl)propyl>-2-<2-(ethoxycarbonyloxy)ethyl>-4,5-dimethoxybenzamid 
• 121654-81-7 2-Cyclohexanecarbonyl-10,11-dimethoxy-2,3,6,7,8,12b-hexahydro-1H-benzo[3,4]azepino[1,2-a]pyrazin-4-one 

Relevant articles and documents

Pd-Catalyzed Regio- and Stereoselective sp3 C?H Arylation of Primary Aliphatic Amines: Mechanistic Studies and Synthetic Applications

The Pd-catalyzed γ-position sp3?C?H arylation of primary amines bearing an aliphatic chain or cycloalkyl substituent and related mechanistic studies are disclosed. 3-Bromo-2-hydroxybenzaldehyde plays a key role in γ-position sp3?C?H arylation as a transient directing group (TDG) to assist the regio- and stereoselective C?H activation of a Pd catalyst, and the development of a tandem reaction to transform 1°-amines into γ-aryl-substituted ketones demonstrates synthetic utility. Density functional theory (DFT)-based calculations revealed the detailed reaction mechanism and the origins of the high selectivity (γ-position and cis-only). The X-ray crystal structure of the isolated endo-palladacycle intermediate supported the DFT results, and a kinetic isotope experiment confirmed the results of DFT calculations indicating that the C?H activation step via simultaneous palladation and deprotonation is rate-determining.

Investigation of dopamine analogues: Synthesis, mechanistic understanding, and structure-property relationship

Dopamine, perhaps the simplest molecule that covalently links catechol and amine, together with its derivatives, has shown impressive adhesive and coating properties with its polymers. However, the scope of the molecules is rather limited, and the polymer

SYNTHESIS OF POLYCYCLIC ALKALOIDS

Disclosed embodiments concern polycyclic alkaloid compounds and methods for their use and synthesis. Particular embodiments concern polycyclic alkaloids having a fused, six-membered ring, while other embodiments concern polycyclic alkaloids having a fused