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3-(3,4-DIMETHOXY-PHENYL)-PROPYLAMINE, also known as DM-PPA, is a chemical compound with the molecular formula C12H19NO2. It is a derivative of phenethylamine and functions as a selective serotonin releasing agent. DM-PPA is primarily utilized in research to explore the impact of serotonin release on the central nervous system. It has demonstrated potential therapeutic applications, particularly in addressing mood disorders and depression, as well as in the regulation of appetite and weight management. This chemical compound has shown promise in various research areas and may hold potential for future clinical applications.

14773-42-3

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14773-42-3 Usage

Uses

Used in Pharmaceutical Research:
3-(3,4-DIMETHOXY-PHENYL)-PROPYLAMINE is used as a research tool for studying the effects of serotonin release on the central nervous system, aiding in the understanding of mood regulation and neurological disorders.
Used in Mood Disorder Treatment:
In the field of psychiatry, 3-(3,4-DIMETHOXY-PHENYL)-PROPYLAMINE is used as a potential therapeutic agent for the treatment of mood disorders, including depression, due to its influence on serotonin levels.
Used in Weight Management:
3-(3,4-DIMETHOXY-PHENYL)-PROPYLAMINE is used as an appetite regulator in the field of nutrition and weight management, potentially aiding in the control of food intake and body weight.
Used in Neurological Research:
In the neuroscience industry, 3-(3,4-DIMETHOXY-PHENYL)-PROPYLAMINE is used as a chemical probe to investigate the role of serotonin in neurological processes and disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 14773-42-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,7,7 and 3 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 14773-42:
(7*1)+(6*4)+(5*7)+(4*7)+(3*3)+(2*4)+(1*2)=113
113 % 10 = 3
So 14773-42-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H17NO2/c1-13-10-6-5-9(4-3-7-12)8-11(10)14-2/h5-6,8H,3-4,7,12H2,1-2H3

14773-42-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(3,4-dimethoxyphenyl)propan-1-amine

1.2 Other means of identification

Product number -
Other names 3,4-Dimethoxy-benzenepropanamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14773-42-3 SDS

14773-42-3Relevant academic research and scientific papers

Pd-Catalyzed Regio- and Stereoselective sp3 C?H Arylation of Primary Aliphatic Amines: Mechanistic Studies and Synthetic Applications

Ha, Hyeonbin,Choi, Ho Jeong,Park, Hahyoun,Gwon, Yunyeong,Lee, Jiin,Kwak, Jaesung,Kim, Min,Jung, Byunghyuck

supporting information, p. 1136 - 1145 (2021/02/12)

The Pd-catalyzed γ-position sp3?C?H arylation of primary amines bearing an aliphatic chain or cycloalkyl substituent and related mechanistic studies are disclosed. 3-Bromo-2-hydroxybenzaldehyde plays a key role in γ-position sp3?C?H arylation as a transient directing group (TDG) to assist the regio- and stereoselective C?H activation of a Pd catalyst, and the development of a tandem reaction to transform 1°-amines into γ-aryl-substituted ketones demonstrates synthetic utility. Density functional theory (DFT)-based calculations revealed the detailed reaction mechanism and the origins of the high selectivity (γ-position and cis-only). The X-ray crystal structure of the isolated endo-palladacycle intermediate supported the DFT results, and a kinetic isotope experiment confirmed the results of DFT calculations indicating that the C?H activation step via simultaneous palladation and deprotonation is rate-determining.

7. 8 - dimethoxy - 2, 3, 4, 5 - tetrahydro - 1 H - benzo [c] azepine hydrochloride and its preparation method (by machine translation)

-

Paragraph 0019; 0027; 0029; 0037, (2017/11/16)

The invention discloses 7, 8 - dimethoxy - 2, 3, 4, 5 - tetrahydro - 1 H - benzo [c] azepine hydrochloride and its preparation method, in order to 3, 4 - dimethoxy c acid as initiator, in thionyl chloride catalytic, then ammonolysis to obtain 3, 4 - dimet

Investigation of dopamine analogues: Synthesis, mechanistic understanding, and structure-property relationship

Hu, Huamin,Dyke, Jason Christopher,Bowman, Brett Allen,Ko, Ching-Chang,You, Wei

, p. 9873 - 9882 (2016/10/07)

Dopamine, perhaps the simplest molecule that covalently links catechol and amine, together with its derivatives, has shown impressive adhesive and coating properties with its polymers. However, the scope of the molecules is rather limited, and the polymer

Diverse alkaloid-like structures from a common building block

Goff, Dane A.

, p. 242 - 256 (2013/01/15)

A wealth of unique enantiopure polycyclic alkaloid-like scaffolds can be prepared on a multigram scale in only a few steps from a common, commercially available intermediate. The attached nitromethyl group can then be used to construct highly diverse func

SYNTHESIS OF POLYCYCLIC ALKALOIDS

-

Paragraph 0204, (2013/09/26)

Disclosed embodiments concern polycyclic alkaloid compounds and methods for their use and synthesis. Particular embodiments concern polycyclic alkaloids having a fused, six-membered ring, while other embodiments concern polycyclic alkaloids having a fused

The palladium-catalyzed preparation of condensed tetracyclic heterocycles and their application to the synthesis of rac-mangochinine

Vincze, Zoltan,Biro, A. Beatrix,Csekei, Marton,Timari, Geza,Kotschy, Andras

, p. 1375 - 1385 (2007/10/03)

Dihydroisoquinoline derivatives and their analogues, prepared by the Bischler-Napieralsky reaction, were converted to their indole-fused derivatives. Scope and limitations of the palladium-catalyzed reaction, proceeding through the tautomeric enamine forms of these compounds, were studied and the process was extended to the preparation of racemic mangochinine. Georg Thieme Verlag Stuttgart.

Dopamine/serotonin receptor ligands VI. Dibenz[gj]-1-oxa-4-azacycloundecene and dibenz[d,g]-2-azacycloundecene: Synthesis of two new heterocyclic ring systems as potential ligands for dopamine receptor subtypes

Wittig, Thomas W.,Enzensperger, Christorph,Lehmann, Jochen

, p. 887 - 898 (2007/10/03)

2-(2-Hydroxyethyl)-N-[2-phenoxyethyl]benzamides and 2-(2-hydroxyethyl)-N-[2-phenylpropyl]benzamides have been prepared from 2-phenoxyethyl- or 2-phenylpropylamines and isochroman-1-one. Applying Bischler-Napieralski reaction, a tetracyclic isoquinolino[2,

Phenylacetamide derivatives and pharmaceutical compositions thereof

-

, (2008/06/13)

The present invention provides novel phenylacetamide derivatives having the following formula STR1 wherein: X is a hydrogen, halogen, hydroxy, nitro, amino, R1, NR1 R2, NHR1 or OR1 wherein R1/su

Novel phenylacetamide derivatives and processes for the preparation thereof

-

, (2008/06/13)

The present invention provides novel phenylacetamide derivatives having the following formula wherein:, X is a hydrogen, halogen, hydroxy, nitro, amino, R1, NR1R2, NHR1 or OR1 wherein R1 and R2 are an optionally substituted C1 8 alky

Synthesis of Isoquinobenzazepines

Meise, Werner,Schlueter, Gerd

, p. 639 - 642 (2007/10/02)

A simple method for the synthesis of 12-alkoxyisoquinobenzazepines 6 in good yields starting from 3-(3-alkoxyphenyl)propylamines 1 and 1-isochromanone (2) is described.

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