16666-81-2Relevant academic research and scientific papers
Silver-Catalysed Hydroarylation of Highly Substituted Styrenes
Dalton, Toryn,Gre?ies, Steffen,Das, Mowpriya,Niehues, Maximilian,Schrader, Malte L.,Gutheil, Christian,Ravoo, Bart Jan,Glorius, Frank
supporting information, p. 8537 - 8541 (2021/03/16)
Hydroarylation is an effective strategy to rapidly increase the complexity of organic structures by transforming flat alkene moieties into three-dimensional frameworks. Many strategies have already been developed to achieve the hydroarylation of styrenes,
P2Y12 receptor antagonists diphenyl thioacetic acid, preparation method and use thereof (by machine translation)
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, (2018/07/06)
The present invention relates to cardiovascular diseases associated with the medicine field. Specifically, the invention relates to a diphenyl thioacetic acid structure of the P2Y12 receptor antagonists, its preparation method and thereof in the preparation of the treatment of cardiovascular diseases in particular thromboembolic disease in the application. Wherein R1 Is selected from H, C1 - C6 Alkyl; R2 Is selected from H, C1 - C6 Alkyl, C3 - C8 A cycloalkyl. (by machine translation)
P2Y12 receptor antagonist for nitrile diphenyl thioacetic acid structure and application of P2Y12 receptor antagonist
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Paragraph 0018; 0019; 0022; 0023, (2018/07/06)
The invention relates to the field of medicines associated with cardiovascular diseases, in particular to a P2Y12 receptor antagonist containing a nitrile diphenyl thioacetic acid structure, a preparation method of the P2Y12 receptor antagonist as well as application of the P2Y12 receptor antagonist in preparing a medicine for treating the cardiovascular diseases, in particular to thromboembolic disease. (The formula is shown in the description).
Novel Synthesis of Conjugated Bisperfluoroalkyl Enynes
Shen, Yanchang,Xiang, Yuejun,Qiu, Weiming
, p. 2965 - 2968 (2007/10/02)
Conjugated bisperfluoroalkyl enynes can be conveniently synthesized in 85-99percent yield by vacuum pyrolysis of (perfluoroacyl)methylene>triphenylphosphoranes which were generated from the corresponding methylene triphenylphosphoranes via double perfluoroacylation in a one-pot reaction.
A novel generation of perfluoroalkylated enolates by reductive cleavage of fluorinated β-ketophosphonium salts
Shen, Yanchang,Xiang, Yuejun,Qiu, Weiming
, p. 4953 - 4954 (2007/10/02)
A novel generation of perfluoroalkylated enolates by reductive cleavage of fluorinated β-ketophosphonium salts and its application to the synthesis of perfluoroalkylated vinyl esters, β-hydroxy ketones, vinyl ether and ketone are described.
A Novel Synthesis of α-Fluoroalkylvinyl- or α-Fluoroepoxyalkyl-phosphonate
Shen, Yanchang,Liao, Qimu,Qiu, Weiming
, p. 695 - 697 (2007/10/02)
α-Fluoroalkylvinyl- or α-fluoroepoxyalkyl-phosphonates can be synthesized by the reaction of diethyl lithium phosphite with fluorinated β-oxoalkylphosphonium salts, depending upon the α-substituents R1 and R2 in the alkylidene moiety of the phosphorane us
SPIROVETIVANES FROM SILYLATED 1-HYDROXYCYCLOPROPANECARBOXALDEHYDE.
Barnier, J. P.,Salauen, J.
, p. 1273 - 1276 (2007/10/02)
The spirodecan-2-one and a spirovetivane, key intermediates of the spirobicyclic sesquiterpenes, have been prepared from silylated 1-vinylcyclopropanols.A selective desilylation of enol ethers is featured.
