16670-59-0

Upstream product

• 328233-91-6 1-methoxy-2-neopentylbenzene 
• 558-17-8 tert-Butyl iodide 
• 95-48-7 ortho-cresol 
• 22526-24-5 1-(2-methoxyphenyl)-2,2-dimethyl-1-propanone 
• 3282-30-2 pivaloyl chloride 
• 33974-41-3 neopentylmagnesium bromide 
• 1404094-79-6 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl (2,2-dimethyl-1-(2-neopentylphenoxy)propyl)carbamate 
• 73526-82-6 2-(2,2-dimethyl-propyl)-phenylamine 

Downstream Products

• 78576-59-7 C₂₃H₃₂O₂ 
• 1417444-13-3 C₂₃H₂₃Cl₂OP 
• 1417444-15-5 C₂₃H₂₃Cl₂P 
• 1417444-11-1 C₁₂H₁₅F₃O₃S 
• 1404094-79-6 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl (2,2-dimethyl-1-(2-neopentylphenoxy)propyl)carbamate 
• 868266-21-1 4-iodo-2-neopentylphenol 

Relevant academic research and scientific papers

Exploiting the modularity of ion-paired chiral ligands for palladium-catalyzed enantioselective allylation of benzofuran-2(3 H)-ones

A highly enantioselective allylation of benzofuran-2(3H)-ones is achieved under Pd catalysis by taking full advantage of the structural modularity of ion-paired chiral ligands.

Versatile approach to α-alkoxy carbamate synthesis and stimulus-responsive alcohol release

A series of α-alkoxy carbamates that cleave under mild conditions to release alcohols has been synthesized through a multicomponent process. The relationship between structural features in these compounds and the rate of alcohol release in the presence of basic hydrogen peroxide has been studied. The preparation of carbamates that cleave under other conditions has been demonstrated.

2-ARYLOXYETHYL GLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS

The present invention relates to certain 2-aryloxyethyl glycine derivatives that exhibit activity as inhibitors of the glycine type-1 transporter, to pharmaceutical compositions containing them and to their use in the treatment of neurological and neuropsychiatric disorder.

Preparation and Reactions of Dianions from the Cresols

With n-BuLi/KO-t-Bu, protons are removed from the hydroxyl and methyl groups of cresols 5 to give dianions 6 in yields of 85percent (ortho), 95percent (meta), and 42percent (para).These dianions react with alkyl halides, Me3SiCl, Bu3SnCl, CO2, and oxidizing agents at carbon only and with dialkyl sulfates at both carbon and oxygen.Thus phenol derivatives bearing primary alkyl groups can be prepared from the corresponding methylphenols via dianions 6.