16673-84-0

Basic information

• Product Name: Benzeneacetamide, N-(1,3-dioxobutyl)-
• CAS NO: 16673-84-0
• Molecular Formula: C12H13NO3
• Molecular Weight: 219.24
• Mol File: 16673-84-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzeneacetamide, N-(1,3-dioxobutyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetamide, N-(1,3-dioxobutyl)-(16673-84-0)
• EPA Substance Registry System: Benzeneacetamide, N-(1,3-dioxobutyl)-(16673-84-0)

Safety Data

• Hazardous Substances Data: 16673-84-0(Hazardous Substances Data)

Upstream product

• 5394-63-8 2,2,6-trimethyl-4H-1,3-dioxin-4-one 
• 103-81-1 Benzeneacetamide 
• 674-82-8 4-methyleneoxetan-2-one 

Downstream Products

• 141883-41-2 2-benzyl-6-methyl-4H-1,3-oxazin-4-one 
• 84334-06-5 3-Acetyl-6-methyl-1-(phenylacetyl)-2,4(1H,3H)-pyridindion 

Relevant articles and documents

Onium Salt-catalyzed Acylations with Diketene

Weak NH- and CH-acids can be acylated advantageously by diketene (1) in the presence of a quarternary ammonium chloride.Carboxamides yield with one or two moles of 1 the products 3 or 10 selectively. β-Keto esters and β-diketones lead to 12a, b or 13, respectively, and acetoacetamides give 5 or 8.The polymer 16 and/or 17 is formed by self-condensation of 1.

Synthesis of N-Acylacetoacetamide using 2,2,6-Trimethyl-1,3-dioxin-4-one

Diketene-acetone adduct (2,2,6-trimethyl-1,3-dioxin-4-one) 1 reacts with amide NH to give the corresponding N-acetoacetates 2.Formamide and basic amides such as picolinamide, on treatment with the adduct, are transformed to the N-acyl-2,6-dimethyl-4-oxo-4H-pyran-3-carboxamide (4a and 4p) together with the corresponding N-acetoacetates.Keywords--diketene-acetone adduct; 1,3-dioxin-4-one; acetylketene; diketene; acetoacetylation; 4-pyrone derivatives; N-acylacetoacetamide

Studies on ketene and its derivatives. XVII. Reaction of diketene with imidates.

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