16681-68-8

Basic information

• Product Name: 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE
• Synonyms: 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE;1H-1,2,3-TRIAZOLE-4-CARBOXALDEHYDE;Nsc20115;2H-1,2,3-Triazole-4-carboxaldehyde;1H-1,2,3-Triazole-5-carboxaldehyde;1,2,3-triazole-4-carbaldehydes;v-Triazole-4-carboxaldehyde;1,2,3-triazole-4-carbaldehyde
• CAS NO: 16681-68-8
• Molecular Formula: C₃H₃N₃O
• Molecular Weight: 97.08
• Mol File: 16681-68-8.mol
• Article Data: 4

Chemical Properties

• Melting Point: 141-142℃
• Boiling Point: 319.3 °C at 760 mmHg
• Flash Point: 151.4 °C
• Appearance: /
• Density: 1.473 g/cm³
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: Acetonitrile (Sparingly), Methanol (Slightly)
• PKA: 6.99±0.70(Predicted)
• CAS DataBase Reference: 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE(16681-68-8)
• EPA Substance Registry System: 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE(16681-68-8)

Safety Data

• Statements: 43
• Safety Statements: 36/37
• Hazardous Substances Data: 16681-68-8(Hazardous Substances Data)

Usage

General Description

1H-[1,2,3]triazole-4-carbaldehyde is a chemical compound with the molecular formula C3H3N3O. It is a derivative of the triazole group, which is a five-membered ring consisting of two carbon atoms and three nitrogen atoms. The compound's structure includes a carbaldehyde functional group, which is a carbon atom double-bonded to an oxygen atom and single-bonded to a hydrogen atom. 1H-[1,2,3]triazole-4-carbaldehyde is used in organic synthesis and is known for its diverse reactivity and ability to participate in a variety of chemical transformations. It has applications in pharmaceuticals, agrochemicals, and material science due to its unique structural and functional properties.

Upstream product

• 872701-03-6 4-(diethoxymethyl)-1H-1,2,3-triazole 
• 624-67-9 Propargylic aldehyde 
• 1398504-71-6 4-(dimethoxymethyl)-1H-1,2,3-triazole 

Downstream Products

• 1175146-24-3 C₁₉H₁₂Cl₂FN₇ 
• 1322616-34-1 (Z)-6-fluoro-3-((1-methyl-1H-1,2,4-triazol-5-yl)methylene)-4-nitroisobenzofuran-1(3H)-one 
• 113934-27-3 1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carbaldehyde 
• 1325725-24-3 1-(2,5-dichlorophenyl)-4-vinyl-1H-1,2,3-triazole 
• 1325725-23-2 1-(3,4-dichlorophenyl)-4-vinyl-1H-1,2,3-triazole 
• 1325725-19-6 1-(4-chlorophenyl)-4-vinyl-1H-1,2,3-triazole 
• 1325725-20-9 1-(4-nitrophenyl)-4-vinyl-1H-1,2,3-triazole 
• 1325725-21-0 1-(4-methoxyphenyl)-4-vinyl-1H-1,2,3-triazole 
• 1240522-58-0 (S)-2-(((1H-1,2,3-triazol-4⁽⁵⁾-yl)methyl)amino)-3-(4-fluorophenyl)-N-(1-methyl-3-(2-(methylamino)pyridin-4-yl)-1H-pyrazol-5-yl)propanamide 
• 1417700-10-7 C₂₃H₂₉N₅O₃ 
• 16681-70-2 1H-1,2,3-triazole-4-carboxylic acid 

Relevant articles and documents

Debenzylation of functionalized 4- and 5-substituted 1,2,3-triazoles

A range of 4- and 5-substituted N-benzyl-1,2,3-triazoles have been submitted to debenzylation using Pd/C and hydrogen in the presence of 1,1,2-trichloroethane. Triazoles with oxygen-containing substituents are efficiently debenzylated under these conditio

Inhibitors of tumor progression loci-2 (Tpl2) kinase and tumor necrosis factor α (TNF-α) production: Selectivity and in vivo antiinflammatory activity of novel 8-substituted-4-anilino-6-aminoquinoline-3- carbonitriles

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