16681-68-8

Usage

Uses

Used in Organic Synthesis:
1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE is used as a key intermediate in organic synthesis for its diverse reactivity and ability to participate in a variety of chemical transformations. Its unique structural and functional properties make it a valuable building block in the creation of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE is used as a starting material or a component in the synthesis of various drugs. Its unique structural features contribute to the development of new pharmaceutical compounds with potential therapeutic applications.
Used in Agrochemical Industry:
1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE is utilized as a precursor in the synthesis of agrochemicals, such as pesticides and herbicides. Its reactivity and structural properties allow for the creation of effective compounds for agricultural applications.
Used in Material Science:
In the field of material science, 1H-[1,2,3]TRIAZOLE-4-CARBALDEHYDE is employed in the development of new materials with specific properties. Its structural and functional characteristics can be leveraged to create materials with tailored characteristics for various applications, such as coatings, adhesives, or polymers.

Upstream product

• 624-67-9 Propargylic aldehyde 
• 872701-03-6 4-(diethoxymethyl)-1H-1,2,3-triazole 
• 1398504-71-6 4-(dimethoxymethyl)-1H-1,2,3-triazole 

Downstream Products

• 16681-70-2 1H-1,2,3-triazole-4-carboxylic acid 
• 1175146-24-3 C₁₉H₁₂Cl₂FN₇ 
• 1417700-10-7 C₂₃H₂₉N₅O₃ 
• 1325725-21-0 1-(4-methoxyphenyl)-4-vinyl-1H-1,2,3-triazole 
• 1325725-20-9 1-(4-nitrophenyl)-4-vinyl-1H-1,2,3-triazole 
• 1325725-19-6 1-(4-chlorophenyl)-4-vinyl-1H-1,2,3-triazole 
• 1325725-23-2 1-(3,4-dichlorophenyl)-4-vinyl-1H-1,2,3-triazole 
• 1325725-24-3 1-(2,5-dichlorophenyl)-4-vinyl-1H-1,2,3-triazole 
• 113934-27-3 1-(4-chlorophenyl)-1H-1,2,3-triazole-4-carbaldehyde 
• 1322616-34-1 (Z)-6-fluoro-3-((1-methyl-1H-1,2,4-triazol-5-yl)methylene)-4-nitroisobenzofuran-1(3H)-one 
• 1240522-58-0 (S)-2-(((1H-1,2,3-triazol-4⁽⁵⁾-yl)methyl)amino)-3-(4-fluorophenyl)-N-(1-methyl-3-(2-(methylamino)pyridin-4-yl)-1H-pyrazol-5-yl)propanamide 

Relevant academic research and scientific papers

Debenzylation of functionalized 4- and 5-substituted 1,2,3-triazoles

A range of 4- and 5-substituted N-benzyl-1,2,3-triazoles have been submitted to debenzylation using Pd/C and hydrogen in the presence of 1,1,2-trichloroethane. Triazoles with oxygen-containing substituents are efficiently debenzylated under these conditio

Selective inhibitors of tumor progression loci-2 (Tpl2) kinase with potent inhibition of TNF-α production in human whole blood

Tpl2 (cot/MAP3K8) is an upstream kinase of MEK in the ERK pathway. It plays an important role in Tumor Necrosis Factor-α (TNF-α) production and signaling. We have discovered that 8-halo-4-(3-chloro-4-fluoro-phenylamino)-6-[(1H-[1,2,3]triazol-4-ylmethyl)-a

Inhibitors of tumor progression loci-2 (Tpl2) kinase and tumor necrosis factor α (TNF-α) production: Selectivity and in vivo antiinflammatory activity of novel 8-substituted-4-anilino-6-aminoquinoline-3- carbonitriles

Tumor progression loci-2 (Tpl2) (Cot/MAP3K8) is a serine/threonine kinase in the MAP3K family directly upstream of MEK. Recent studies using Tpl2 knockout mice have indicated an important role for Tpl2 in the lipopolysaccharide (LPS) induced production of

1,3-Dipolar cycloaddition of trimethylsilyl azide to propynals and dimerization of 1H-1,2,3-triazole-5-carbaldehydes to tricyclic bis-hemiaminals

Reactions of trimethylsilyl azide with 3-trimethylsilyl-2-propynal and 2-propynal were studied. X-Ray analysis of the molecular structure of 4-trimethylsilyl-1H-1,2,3-triazole-5-carbaldehyde showed that the carbonyl group appears in the s-cis conformation