166815-97-0 Usage
Molecular Weight
335.42 g/mol The molecular weight of the compound is 335.42 g/mol, calculated based on the atomic weights of the elements in the molecular formula.
Structure
COOCH2CH3 The structure of 2-(1-Boc-piperidin-4-ylMethyl)Malonic acid diethyl ester consists of a malonic acid backbone with a piperidine ring attached to the methyl group, and a Boc protecting group attached to the piperidine ring. The compound is a diethyl ester, with two ethyl groups esterified to the carbonyl group.
Boc Protecting Group
(tert-butoxycarbonyl) The Boc protecting group is a tert-butoxycarbonyl group (-BOC) attached to the piperidine ring in the compound. This protecting group is commonly used in organic synthesis to protect amine groups from unwanted reactions.
Reactivity
Nucleophilic addition and substitution 2-(1-Boc-piperidin-4-ylMethyl)Malonic acid diethyl ester is capable of undergoing a variety of chemical reactions, such as nucleophilic addition and substitution, due to the presence of the active ester and amine groups in the molecule.
Applications
Pharmaceutical and biologically active molecules The compound is commonly used as a reagent in the preparation of various pharmaceutical and biologically active molecules. It is also used as a building block in the synthesis of complex organic compounds.
Potential Drug Development
New drugs and pharmaceuticals 2-(1-Boc-piperidin-4-ylMethyl)Malonic acid diethyl ester has potential applications in the development of new drugs and pharmaceuticals due to its reactivity and ability to be used as a building block in complex organic synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 166815-97-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,8,1 and 5 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 166815-97:
(8*1)+(7*6)+(6*6)+(5*8)+(4*1)+(3*5)+(2*9)+(1*7)=170
170 % 10 = 0
So 166815-97-0 is a valid CAS Registry Number.
InChI:InChI=1/C18H31NO6/c1-6-23-15(20)14(16(21)24-7-2)12-13-8-10-19(11-9-13)17(22)25-18(3,4)5/h13-14H,6-12H2,1-5H3
166815-97-0Relevant articles and documents
Palladium-Catalyzed Atom-Transfer Radical Cyclization at Remote Unactivated C(sp3)?H Sites: Hydrogen-Atom Transfer of Hybrid Vinyl Palladium Radical Intermediates
Ratushnyy, Maxim,Parasram, Marvin,Wang, Yang,Gevorgyan, Vladimir
, p. 2712 - 2715 (2018/03/02)
A novel mild, visible-light-induced palladium-catalyzed hydrogen atom translocation/atom-transfer radical cyclization (HAT/ATRC) cascade has been developed. This protocol involves a 1,5-HAT process of previously unknown hybrid vinyl palladium radical intermediates, thus leading to iodomethyl carbo- and heterocyclic structures.
1-PHENYLALKANONE 5-HT4 RECEPTOR LIGANDS
-
, (2008/06/13)
The present invention relates to novel 5-HT 4 receptor ligands which are 1-(5-halo-4-aminophenyl) (C 2-6)alkan-1-one derivatives in which the 5-halo-4-aminophenyl group is substituted at its 2-position with (C 1-4)alkyloxy or phenyl(C 1-4)alkyloxy and optionally substituted at its 3-position with (C 1-4)alkyloxy or substituted at its 2-and 3-positions together with methylenedioxy or ethylenedioxy and the highest numbered carbon of the (C 2-6)alkan-1-one is substituted with di(C 1-4)alkylamino, morpholin-1-yl or pyrrolidin-1-yl or optionally substituted piperidin-1-yl, piperidin-4-yl, azacyclohept-1-yl, azabicyclo[2.2.1]hept-3-yl, azabicylo[2.2.2]oct-3-yl or azabicylo[3.2. 2] non-3-yl; and the pharmaceutically acceptable salts, individual isomers and mixtures of isomers and methods of using and making such derivatives.
