166819-06-3Relevant academic research and scientific papers
Synthesis, Structure Elucidation, and Biochemical Evaluation of 7α- and 7β-Arylaliphatic-Substituted Androst-4-ene-3,17-diones as Inhibitors of Aromatase
O'Reilly, Jill M.,Li, Naiyin,Duax, William L.,Brueggemeier, Robert W.
, p. 2842 - 2850 (1995)
The inhibition of aromatase, the cytochrome P450 enzyme complex responsible for the conversion of androgens to estrogens, may be useful for the endocrine treatment of breast cancer.Previously, several 7α-thio-substituted androstenediones have been shown t
