
Journal of Medicinal Chemistry p. 2842 - 2850 (1995)
Update date:2022-08-04
Topics:
O'Reilly, Jill M.
Li, Naiyin
Duax, William L.
Brueggemeier, Robert W.
The inhibition of aromatase, the cytochrome P450 enzyme complex responsible for the conversion of androgens to estrogens, may be useful for the endocrine treatment of breast cancer.Previously, several 7α-thio-substituted androstenediones have been shown t
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