166830-09-7

Basic information

• Product Name: 2',3'-dideoxy-3'-C--β-D-erythropentopyranosyl thymine
• CAS NO: 166830-09-7
• Molecular Weight: 528.605
• Mol File: 166830-09-7.mol

Chemical Properties

• CAS DataBase Reference: 2',3'-dideoxy-3'-C--β-D-erythropentopyranosyl thymine(CAS DataBase Reference)
• NIST Chemistry Reference: 2',3'-dideoxy-3'-C--β-D-erythropentopyranosyl thymine(166830-09-7)
• EPA Substance Registry System: 2',3'-dideoxy-3'-C--β-D-erythropentopyranosyl thymine(166830-09-7)

Safety Data

• Hazardous Substances Data: 166830-09-7(Hazardous Substances Data)

Upstream product

• 166830-06-4 2',3'-dideoxy-3'-C-hydroxymethyl-β-D-erythro-pentopyranosyl thymine 
• 14470-28-1 mono-4-methoxytrityl chloride 

Downstream Products

• 166830-12-2 1-{(R)-4-[(4-Methoxy-phenyl)-diphenyl-methoxymethyl]-3,6-dihydro-2H-pyran-2-yl}-5-methyl-1H-pyrimidine-2,4-dione 

Relevant articles and documents

3'-Deoxy-3'-hydroxymethyl-aldopentopyranosyl nucleoside synthesis. Part I

A straightforward synthesis of 3'-deoxy-3'-hydroxymethyl-aldopentopyranosyl nucleosides is described starting from β-D-xylopyranosyl nucleosides. β-D-xylopyranosyl thymine 17a,b,c, and uracil 17d are converted into the 4'-benzoylated derivatives 18a,b and further into the 2',3'-enepyranosyl compounds 19b,c. A 3'-hydroxymethyl appendix has been introduced using a free-radical methodology to furnish 20a,b. Inversion of configuration of the 4'-position yielded the target nucleosides 22a,b. X-ray and 1H NMR conformation analysis prove the equatorial orientation of the base moiety in the target compounds.