166900-21-6

Basic information

• Product Name: S-(2-acetamidoethyl) (RS)3-hydroxybutanethioate
• CAS NO: 166900-21-6
• Molecular Weight: 205.278
• Mol File: 166900-21-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: S-(2-acetamidoethyl) (RS)3-hydroxybutanethioate(CAS DataBase Reference)
• NIST Chemistry Reference: S-(2-acetamidoethyl) (RS)3-hydroxybutanethioate(166900-21-6)
• EPA Substance Registry System: S-(2-acetamidoethyl) (RS)3-hydroxybutanethioate(166900-21-6)

Safety Data

• Hazardous Substances Data: 166900-21-6(Hazardous Substances Data)

Upstream product

• 23255-41-6 3-oxobutanoyl-N-acetylcysteamine thioester 
• 1190-73-4 2-(acetylamino)ethanethiol 
• 300-85-6 3-Hydroxybutyric acid 

Relevant articles and documents

An Unusual Type II Polyketide Synthase System Involved in Cinnamoyl Lipid Biosynthesis

As a unique structural moiety in natural products, cinnamoyl lipids (CLs), are proposed to be assembled by unusual type II polyketide synthases (PKSs). Herein, we demonstrate that the assembly of the CL compounds youssoufenes is accomplished by a PKS system that uniquely harbors three phylogenetically different ketosynthase/chain length factor (KS/CLF) complexes (YsfB/C, YsfD/E, and YsfJ/K). Through in vivo gene inactivation and in vitro reconstitution, as well as an intracellular tagged carrier-protein tracking (ITCT) strategy developed in this study, we successfully elucidated the isomerase-dependent ACP-tethered polyunsaturated chain elongation process. The three KS/CLFs were revealed to modularly assemble different parts of the youssoufene skeleton, during which benzene ring closure happens right after the formation of an ACP-tethered C18 polyene. Of note, the ITCT strategy could significantly contribute to the elucidation of other carrier-protein-dependent biosynthetic machineries.