166903-23-7

Upstream product

• 137348-63-1 2--N''-<(S)-α-methylbenzyl>acetamide 
• 137348-67-5 2-amino-N'-(α-phenylethyl)acetamide 
• 98-88-4 benzoyl chloride 
• 137348-64-2 2-N-(2,2'-dimethylpropyliden)amino-N'-(α-phenylethyl)acetamide 
• 93-97-0 benzoic acid anhydride 

Downstream Products

• 137348-68-6 (R)-1-benzoyl-2-tert-butyl-3(H)-1,3-imidazolidin-4-one 
• 101055-57-6 (2R)-1-benzoyl-2-(1,1-dimethylethyl)-3-methyl-4-imidazolidinone 

Relevant academic research and scientific papers

Highly enantioselective synthesis of (R)- and (S)-2-amino-5-phosphonopentanoic acids [(R)- and (S)-AP5] via modified Seebach imidazolidinones

The preparation of four new stereoisomeric 1-carbobenzyloxy-2-tert-butyl-3-(α-methylbenzyl)-1,3-imidazolidin-4-o nes is described. Alkylation of the lithium enolates of these chiral glycine derivatives proceeds with high diastereoselectivity. In particula

Alternative Method for the Resolution of 1-Benzoyl-2-tert-butyl-3-methyl-1,3-imidazolidin-4-one

The title heterocycles, which are useful chiral precursors for the asymmetric synthesis of α-amino acids, an be prepared in enantiomerically pure form via the separation of diastereomeric derivatives incorporating (S)-α-methyl-benzylamine.