16691-19-3Relevant articles and documents
Catalytic asymmetric propargyl- and allylboration of hydrazonoesters: a metal-free approach to sterically encumbered chiral α-amino acid derivatives
Jonker, Sybrand J. T.,Diner, Colin,Schulz, G?ran,Iwamoto, Hiroaki,Eriksson, Lars,Szabó, Kálmán J.
, p. 12852 - 12855 (2018)
A new asymmetric catalytic propargyl- and allylboration of hydrazonoesters is reported. The reactions utilize allenyl- and allylboronic acids in the presence of the inexpensive parent BINOL catalyst. The reactions can be performed under mild conditions (0 °C) without any metal catalyst or other additives affording sterically encumbered chiral α-amino acids. This is the first metal-free method for the asymmetric propargyl- and allylboration of hydrazonoesters.
Asymmetric Br?nsted acid catalyzed cycloadditions-efficient enantioselective synthesis of pyrazolidines, pyrazolines, and 1,3-diamines from N-acyl hyrazones and alkenes
Rueping, Magnus,Maji, Modhu Sudan,Kü?ük, Hatice Ba?pínar,Atodiresei, Iuliana
supporting information, p. 12864 - 12868 (2013/02/22)
A general, metal-free, highly enantioselective Bronsted acid catalyzed [3+2] cycloaddition between hydrazones and alkenes has been developed that affords pyrazolidine derivatives (see scheme). The resulting optically active pyrazolidines can undergo many chemical transformations which allow, for example, the enantioselective synthesis of valuable pyrazolines and 1,3-diamines. Copyright
