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166953-18-0

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166953-18-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 166953-18-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,6,9,5 and 3 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 166953-18:
(8*1)+(7*6)+(6*6)+(5*9)+(4*5)+(3*3)+(2*1)+(1*8)=170
170 % 10 = 0
So 166953-18-0 is a valid CAS Registry Number.

166953-18-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-pyridin-4-ylpiperazin-2-one

1.2 Other means of identification

Product number -
Other names 1-(4-pyridinyl)piperazin-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:166953-18-0 SDS

166953-18-0Relevant articles and documents

Discovery of Potent EV71 Capsid Inhibitors for Treatment of HFMD

Li, Peng,Yu, Jun,Hao, Fei,He, Haiying,Shi, Xuyang,Hu, Jiao,Wang, Li,Du, Chunyan,Zhang, Xiao,Sun, Ya,Lin, Fusen,Gu, Zhengxian,Xu, Deming,Chen, Xinsheng,Shen, Liang,Hu, Guoping,Li, Jian,Chen, Shuhui,Xiao, Wei,Wang, Zhenzhong,Guo, Qingming,Chang, Xiujuan,Tian, Xuyang,Lin, Tianwei

, p. 841 - 846 (2017)

Enterovirus 71 (EV71) is a major causative agent of hand, foot, and mouth disease (HFMD), which can spread its infections to the central nervous and other systems with severe consequences. The viral caspid protein VP1 is a well-known target for antiviral efficacy because its occupancy by suitable compounds could stabilize the virus capsid, thus preventing uncoating of virus for RNA release. In this Letter, design, synthesis, and biological evaluation of novel anti-EV71 agents (aminopyridyl 1,2,5-thiadiazolidine 1,1-dioxides) are described. One of the most promising compounds (14) showed excellent antiviral activity against EV71 (EC50 = 4 nM) and exhibited excellent in vivo efficacy in the EV71 infected mouse model.

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