166964-09-6

Basic information

• Product Name: 5-AMINO-4-CHLORO-3-METHYLISOXAZOLE
• Synonyms: 4-CHLORO-3-METHYL-5-ISOXAZOLAMINE;5-AMINO-4-CHLORO-3-METHYLISOXAZOLE;4-chloro-3-Methylisoxazol-5-aMine;5-AMino-4-Chloro-3-Mythylisoxazole;4-Chloro-3-methylisoxazol-5-amine, 4-Chloro-3-methyl-1,2-oxazol-5-amine;4-Chloro-3-Methyl-isoxazol-5-ylaMine
• CAS NO: 166964-09-6
• Molecular Formula: C₄H₅ClN₂O
• Molecular Weight: 132.55
• Mol File: 166964-09-6.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 245.105 °C at 760 mmHg
• Flash Point: 102.036 °C
• Appearance: /
• Density: 1.381 g/cm³
• Vapor Pressure: 0.029mmHg at 25°C
• Refractive Index: 1.551
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 5-AMINO-4-CHLORO-3-METHYLISOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINO-4-CHLORO-3-METHYLISOXAZOLE(166964-09-6)
• EPA Substance Registry System: 5-AMINO-4-CHLORO-3-METHYLISOXAZOLE(166964-09-6)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 22
• HazardClass: IRRITANT
• Hazardous Substances Data: 166964-09-6(Hazardous Substances Data)

Usage

Description

5-Amino-4-Chloro-3-Methylisoxazole, also known as 4-Chloro-3-methyl-5-isoxazolamine, is a chemical compound that is recognized in the field of chemistry for its unique structure. It is composed of elements such as nitrogen, chlorine, carbon, hydrogen, and oxygen, which are organized in a specific configuration. 5-AMINO-4-CHLORO-3-METHYLISOXAZOLE is often used in advanced chemical research and development, and it is essential to handle it with appropriate safety measures due to potential hazards.

Uses

Used in Chemical Research and Development:
5-Amino-4-Chloro-3-Methylisoxazole is used as a research compound for its unique chemical properties. It is employed in various chemical studies to explore its potential applications and interactions with other compounds.
Used in Pharmaceutical Industry:
5-Amino-4-Chloro-3-Methylisoxazole is used as a building block or intermediate in the synthesis of pharmaceutical compounds. Its unique structure and properties make it a valuable component in the development of new drugs and therapeutic agents.
Used in Material Science:
5-Amino-4-Chloro-3-Methylisoxazole is used as a component in the development of new materials with specific properties. Its incorporation into materials can lead to the creation of novel compounds with unique characteristics, such as improved stability or enhanced reactivity.
Used in Environmental Applications:
5-Amino-4-Chloro-3-Methylisoxazole is used in environmental research to study its potential role in the remediation of contaminated sites or the development of new environmental technologies. Its unique chemical properties may contribute to the creation of innovative solutions for environmental challenges.

InChI:InChI=1/C4H5ClN2O/c1-2-3(5)4(6)8-7-2/h6H2,1H3

Upstream product

• 14678-02-5 5-amino-3-methylisoxazole 
• 128-09-6 N-chloro-succinimide 

Downstream Products

• 184644-72-2 3-{[(4-chloro-3-methyl-5-isoxazolyl)amino]sulfonyl}-2-thiophenecarboxylic acid methyl ester 

Relevant articles and documents

SUBSTITUTED THIOPHENES

Disclosed herein are substituted pyrimidine-based endothelin modulators of Formula I, processes of preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.

N-heteroaryl aryl-substituted thienyl-furyl-and pyrrolyl-sulfonamides and derviatives thereof that modulate the activity of endothelin

Thienyl-, furyl- and pyrrolyl-sulfonamides, formulations of pharmaceutically-acceptable salts thereof and methods for modulating or altering the activity of the endothelin family of peptides are provided. In particular, N-(isoxazolyl)thienylsulfonamides, N-(isoxazolyl)furylsulfonamides and N-(isoxazolyl)pyrrolylsulfonamides, formulations thereof and methods using these sulfonamides for inhibiting the binding of an endothelin peptide to an endothelin receptor by contacting the receptor with the sulfonamide are provided. Methods for treating endothelin-mediated disorders by administering effective amounts of one or more of these sulfonamides or prodrugs thereof that inhibit the activity of endothelin are also provided.

N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin

Thienyl-, furyl- and pyrrolyl-sulfonamides and methods for modulating or altering the activity of the endothelin family of peptides are provided. In particular, N-(isoxazolyl)thienylsulfonamides, N-(isoxazolyl)furylsulfonamides and N-(isoxazolyl)pyrrolylsulfonamides and methods using these sulfonamides for inhibiting the binding of an endothelin peptide to an endothelin receptor by contacting the receptor with the sulfonamide are provided. Methods for treating endothelin-mediated disorders by administering effective amounts of one or more of these sulfonamides or prodrugs thereof that inhibit or increase the activity of endothelin are also provided.